QBD10203

TFP-dPEG^®₄-biotinidase resistant biotin

• Fórmula empírica (Notação de Hill): C₃₁H₄₄F₄N₄O₉S
• Peso molecular: 724.76
• Código UNSPSC: 51171641
• ID de substância PubChem: 329823892
• NACRES: NA.22

Propriedades

• Ensaio: >90%
• Formulário: solid or viscous liquid
• adequação da reação: reagent type: cross-linking reagent; reaction type: Biotinylations; reactivity: amine reactive; reagent type: linker
• arquitetura do polímero: shape: linear; functionality: heterobifunctional
• Condições de expedição: ambient
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O=C1NC(C2N1)CSC2CCCCC(NC(C(NCCOCCOCCOCCOCCC(OC3=C(C(F)=CC(F)=C3F)F)=O)=O)CC)=O
• InChI: 1S/C31H44F4N4O9S/c1-2-21(37-24(40)6-4-3-5-23-28-22(18-49-23)38-31(43)39-28)30(42)36-8-10-45-12-14-47-16-15-46-13-11-44-9-7-25(41)48-29-26(34)19(32)17-20(33)27(29)35/h17,21-23,28H,2-16,18H2,1H3,(H,36,42)(H,37,40)(H2,38,39,43)
• chave InChI: IOOKENPHEAMTTM-UHFFFAOYSA-N

Descrição

Características e benefícios

TFP-dPEG^®₄-biotinidase resistant biotin contains an amine reactive TFP ester and chemically modified biotin that is stable in the presence of biotinidase. Resistance to biotinidase cleavage of biotin is necessary in some biotechnology applications. The chemical modification to biotin imparts resistance to biotinidase cleavage without reducing the strength of biotin-avidin binding. The single molecular weight dPEG^® spacer imparts water solubility, prevents aggregation and precipitation of labeled peptides and proteins, and reduces non-specific binding. Two different single molecular weight dPEG^® spacers are available for precise spatial control between the modified biotin and the surface of the molecule to which it is conjugated.

Informações legais

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable