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Merck
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Documentos Principais

E40609

Sigma-Aldrich

Ethyl nicotinate

99%

Sinônimo(s):

Nicotinic acid ethyl ester

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About This Item

Fórmula empírica (Notação de Hill):
C8H9NO2
Número CAS:
Peso molecular:
151.16
Beilstein:
122937
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de substância PubChem:
NACRES:
NA.22

Nível de qualidade

Ensaio

99%

Formulário

liquid

índice de refração

n20/D 1.504 (lit.)

p.e.

223-224 °C (lit.)

pf

8-10 °C (lit.)

densidade

1.107 g/mL at 25 °C (lit.)

cadeia de caracteres SMILES

CCOC(=O)c1cccnc1

InChI

1S/C8H9NO2/c1-2-11-8(10)7-4-3-5-9-6-7/h3-6H,2H2,1H3

chave InChI

XBLVHTDFJBKJLG-UHFFFAOYSA-N

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Pictogramas

CorrosionExclamation mark

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

8A - Combustible corrosive hazardous materials

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

199.4 °F - closed cup

Ponto de fulgor (°C)

93 °C - closed cup

Equipamento de proteção individual

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Kenji Sugibayashi et al.
Drug metabolism and pharmacokinetics, 19(5), 352-362 (2004-11-19)
The simultaneous diffusion and metabolism of ethyl nicotinate (EN) in a cultured human skin model, Living Skin Equivalent-high, was evaluated by the in vitro skin permeation and metabolism experiments, and esterase distribution was also determined. Theoretical calculations using Fick's 2nd
Tanasait Ngawhirunpat et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 58(3), 645-651 (2004-09-29)
The skin transport and metabolism characteristics of ethyl nicotinate (EN) in rabbit, rat, guinea-pig, pig, shed snake skin and human were compared. In vitro skin transport using excised skin and hydrolysis experiments using skin homogenate were carried out. Flux of
Tanasait Ngawhirunpat et al.
Biological & pharmaceutical bulletin, 26(9), 1311-1314 (2003-09-03)
The age and species dependent characteristics of cutaneous esterase activity were examined in cultured keratinocytes of neonatal and adult humans and of rats at the age of 1, 3, 10, and 50 d. The existence of esterases was characterized using
Zuleikha A M Nworgu et al.
Acta poloniae pharmaceutica, 64(2), 179-182 (2007-08-02)
3-Carbomethoxypyridine (CMP) was isolated and characterized from the leaves of Pyrenacantha staudtii Hutch and Dalz, family Icacinaceae, in our earlier study and was found to possess an inhibitory activity on the isolated rat uterus. In order to study the structure
Adel S Girgis et al.
European journal of medicinal chemistry, 43(9), 1818-1827 (2008-02-05)
2-(alicyclic-amino)-4,6-diaryl-3-pyridinecarboxylates 5a-d were prepared via aromatic nucleophilic substitution reaction of secondary amines (piperidine or morpholine) with 2-bromo-3-pyridinecarboxylate derivatives 3a,b. The latters were obtained through bromination of 3-aryl-4-benzoyl-2-cyanobutyrates 2a and 2b, which were obtained from the base promoted addition of ethyl

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