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B10102

Sigma-Aldrich

Benzo[e]pyrene

98%

Sinônimo(s):

1,2-Benzpyrene, 4,5-Benzpyrene

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About This Item

Fórmula empírica (Notação de Hill):
C20H12
Número CAS:
192-97-2
Peso molecular:
252.31
Beilstein:
1911334
Número CE:
205-892-7
Número MDL:
MFCD00003605
Código UNSPSC:
12352103
ID de substância PubChem:
24891539
NACRES:
NA.23

Ensaio

98%

forma

crystals

pf

177-180 °C (lit.)

cadeia de caracteres SMILES

c1ccc2c(c1)c3cccc4ccc5cccc2c5c34

InChI

1S/C20H12/c1-2-8-16-15(7-1)17-9-3-5-13-11-12-14-6-4-10-18(16)20(14)19(13)17/h1-12H

chave InChI

TXVHTIQJNYSSKO-UHFFFAOYSA-N

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Descrição geral

This polycyclic aromatic hydrocarbon is soluble in acetone. It is a non-carcinogenic benzopyrene isomer. Studies report its lack of immunosuppressive activity following in vivo and in vitro exposure.In nature, it is metabolized by strains of C. elegans to 3-benzo[e]Pyrene sulphate, 1-hydroxy-3-benzi[e]pyrenyl sulfate and bezo[e]Pyrene 3-O-ß-glucopyranoside.

Aplicação

Used for studies of immune suppressive activity of bezo[e]Pyrene on antibody response to DNP-Ficoll and sheep erythrocytes and "dispersive liquid -liquid micro extraction” technique by extracting organic compounds from water samples.

Pictogramas

Health hazardEnvironment
GHS08,GHS09

Palavra indicadora

Danger

Frases de perigo

H350,H410

Declarações de precaução

P201 - P273 - P308 + P313

Classificações de perigo

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificados de análise (COA)

Lot/Batch Number
MKCP5010
MKCF2578
MKBX6087V
MKBX2505V
MKBW6170V

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Benzo[a]pyrene-d12 98 atom % D

Sigma-Aldrich

451797

Benzo[a]pyrene-d12

K L White et al.
Cancer research, 44(8), 3388-3393 (1984-08-01)
The role of metabolic activation of benzo(a)pyrene B(a)P in mediating its suppression of humoral immune responsiveness of the female C57BL/6 X C3H F1 (hereafter called B6C3F1) mouse was addressed in these studies. The model was the in vitro antibody response
Mohammad Rezaee et al.
Journal of chromatography. A, 1116(1-2), 1-9 (2006-04-01)
A new microextraction technique termed dispersive liquid-liquid microextraction (DLLME) was developed. DLLME is a very simple and rapid method for extraction and preconcentration of organic compounds from water samples. In this method, the appropriate mixture of extraction solvent (8.0 microL
D W Rosenberg et al.
Archives of biochemistry and biophysics, 300(1), 186-192 (1993-01-01)
The consequences of altered cytochrome P450-dependent monooxygenase activities in colonic tissue are unknown. As an initial step toward elucidating underlying mechanisms that regulate cytochrome P450 levels in colonic epithelium, we have characterized CYP1A1(3) induction in cultured human colonic cells (Caco-2).
S Faiderbe et al.
Cancer research, 52(10), 2862-2865 (1992-05-15)
High levels of anti-phosphatidylinositol (PtdIns) autoantibodies (autoAb) have been previously described in sera of cancer patients and in plasma of dimethylbenzanthracene-treated female Sprague-Dawley rats. The presence of anti-PtdIns autoAb was tested in a model of highly malignant sarcomas induced by
K Sterling et al.
Toxicology and applied pharmacology, 128(1), 18-24 (1994-09-01)
Hepa 1c1c7 (WT), TAOc1BPrc1 (CI), and BPrc1 (CII) mouse hepatoma cells were exposed to benzo[e]pyrene (B[e]P) or benzo[a]pyrene (B[a]P). B[e]P induced activity of a rat CYP1A1 reporter gene construct (-3015 to +2545 bp) by 1.8- to 2-fold and 5-fold in
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