936588

(S,R,S)-AHPC-acetamido-O-PEG2-C1-acid

≥95%

• Sinônimo(s): (4R)-N-[2-[2-[2-(Carboxymethoxy)ethoxy]ethoxy]acetyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide, (S)-13-[(2S,4R)-4-Hydroxy-2-[[4-(4-methylthiazol-5-yl)benzyl]carbamoyl]pyrrolidin-1-ylcarbonyl]-14,14-dimethyl-11-oxo-3,6,9-trioxa-12-azapentadecanoic acid, (S)-13-[(2S,4R)-4-Hydroxy-2-[[4-(4-methylthiazol-5-yl)benzyl]carbamoyl]pyrrolidine-1-carbonyl]-14,14-dimethyl-11-oxo-3,6,9-trioxa-12-azapentadecanoic acid, L-Prolinamide, N-[2-[2-[2-(carboxymethoxy)ethoxy]ethoxy]acetyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
• Fórmula empírica (Notação de Hill): C₃₀H₄₂N₄O₉S
• Número CAS: 2172820-10-7
• Peso molecular: 634.74
• Número MDL: MFCD33020891
• Código UNSPSC: 12352106
• NACRES: NA.22

Propriedades

• ligand: VH032
• Nível de qualidade: 100
• Ensaio: ≥95%
• Formulário: powder or crystals
• cor: white to beige
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: C([C@@H](NC(COCCOCCOCC(O)=O)=O)[C@](C)(C)C)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1
• InChI: 1S/C30H42N4O9S/c1-19-26(44-18-32-19)21-7-5-20(6-8-21)14-31-28(39)23-13-22(35)15-34(23)29(40)27(30(2,3)4)33-24(36)16-42-11-9-41-10-12-43-17-25(37)38/h5-8,18,22-23,27,35H,9-17H2,1-4H3,(H,31,39)(H,33,36)(H,37,38)/t22-,23+,27-/m1/s1
• chave InChI: IVARPPZGMUAWCE-QSEAXJEQSA-N

Descrição

Aplicação

(S,R,S)-AHPC-acetamido-O-PEG2-C1-acid is a functionalized von Hippel-Lindau (VHL) ligand. It contains a terminal carboxyl group for conjugation with amine linkers. A basic building block for development of a protein degrader library.

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Informações legais

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable