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900649

Sigma-Aldrich

Methoxy poly(ethylene glycol)-block-poly(ε-caprolactone)

2k-2k

Sinônimo(s):

mPEG-b-PCL, mPEG-PCL

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About This Item

Fórmula linear:
CH3O(CH2CH2O)n(COCH2CH2CH2CH2CH2O)mH
Código UNSPSC:
12161904
NACRES:
NA.23

Nível de qualidade

100

forma

powder

peso molecular

PCL average Mn ~2,000
PEG average Mn ~2,000

temperatura de transição

flash point >230 °F
Tm 47-51 °C

temperatura de armazenamento

2-8°C

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Aplicação

Biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block. These materials have been used as a block copolymer surfactant as well as in control release and nanoparticle formulation for drug delivery applications. Well-defined materials with varying properties can be prepared by controlling the relative length of each polymer block. Hydroxyl termination allows for facile further chemical modification of these materials.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

>230.0 °F

Ponto de fulgor (°C)

> 110 °C

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On the mechanism of formation of vesicles from poly(ethylene oxide)-block-poly(caprolactone) copolymers.
Adams DJ, et al.
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Timolol maleate (TM) has been used for many years for the reduction of intraocular pressure (IOP) in glaucoma patients. However, the topical mode of administration (eyedrops) is far from optimal because of the issues of low bioavailability, high drug wastage
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Artigos

Polymersomes for Drug Delivery

The development of drugs that target specific locations within the human body remains one of the greatest challenges in biomedicine today.

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