77386
2-Bromo-1-ethyl-pyridinium tetrafluoroborate
≥97.0% (T)
Sinônimo(s):
BEP
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About This Item
Fórmula empírica (Notação de Hill):
C7H9BBrF4N
Número CAS:
Peso molecular:
273.86
Beilstein:
4059265
Número CE:
Número MDL:
Código UNSPSC:
12352005
ID de substância PubChem:
NACRES:
NA.22
Produtos recomendados
Nível de qualidade
Ensaio
≥97.0% (T)
Formulário
crystals
adequação da reação
reaction type: Coupling Reactions
pf
103-107 °C
aplicação(ões)
peptide synthesis
grupo funcional
bromo
cadeia de caracteres SMILES
F[B-](F)(F)F.CC[n+]1ccccc1Br
InChI
1S/C7H9BrN.BF4/c1-2-9-6-4-3-5-7(9)8;2-1(3,4)5/h3-6H,2H2,1H3;/q+1;-1
chave InChI
YJDXVQLBIAJTHP-UHFFFAOYSA-N
Descrição geral
2-Bromo-1-ethyl-pyridinium tetrafluoroborate is a coupling reagent employed in the synthesis of amides and esters through amidation and esterification reactions, respectively. It is generally prepared by the reaction of triethyloxonium tetrafluoroborate with 2?bromo pyridine.
Aplicação
2-Bromo-1-ethyl-pyridinium tetrafluoroborate can be used as a coupling reagent for:
- The synthesis of N-methylated peptides in solution and solid phase.
- The synthesis of cyclosporin A fragment and dolastatin 15 pentapeptide moiety.
Outras notas
Coupling reagent for peptide synthesis; less racemization and faster reaction than with other reagents;e.g. BOP, PyBrOP, PyClU, BTFFH, CMBI
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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