75666

5-(Benzylthio)-1H-tetrazole

≥99.0% (HPLC)

• Sinônimo(s): 5-Benzylmercapto-1,2,3,4-tetrazole, 5-Benzylmercaptotetrazole, 5-Benzylthio-1H-tetrazole, 5-[(Phenylmethyl)thio]-2H-tetrazole
• Fórmula empírica (Notação de Hill): C₈H₈N₄S
• Número CAS: 21871-47-6
• Peso molecular: 192.24
• Número MDL: MFCD00068731
• Código UNSPSC: 12352100
• ID de substância PubChem: 57652580
• NACRES: NA.22

Propriedades

• Ensaio: ≥99.0% (HPLC)
• Formulário: crystals
• pf: 135-138 °C (DSC-onset)
• grupo funcional: phenyl; thioether
• cadeia de caracteres SMILES: C(Sc1nnn[nH]1)c2ccccc2
• InChI: 1S/C8H8N4S/c1-2-4-7(5-3-1)6-13-8-9-11-12-10-8/h1-5H,6H2,(H,9,10,11,12)
• chave InChI: GXGKKIPUFAHZIZ-UHFFFAOYSA-N

Descrição

Descrição geral

5-(Benzylthio)-1H-tetrazole (BTT activator) is an organic compound that is used as an activator in the synthesis of oligonucleotides. The activator reacts with the phosphoramidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′-hydroxyl group of the growing oligonucleotide chain.

Outras notas

Activator for DNA synthesis; superior alternative to tetrazole

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves