746118

Sodium difluoroheptylazidosulfinate

95%

• Sinônimo(s): Baran DAAS-Na Reagent, Sodium 1,1-difluoro-7-azido-heptylsulfinate, Sodium 7-azido-1,1-difluoroheptanesulfinate
• Fórmula empírica (Notação de Hill): C₇H₁₂F₂N₃NaO₂S
• Número CAS: 1450912-63-6
• Peso molecular: 263.24
• Código UNSPSC: 12352125
• ID de substância PubChem: 329765744
• NACRES: NA.22

Propriedades

• Nível de qualidade: 100
• Ensaio: 95%
• forma: solid
• adequação da reação: reaction type: C-C Bond Formation; reagent type: catalyst; reaction type: C-H Activation; reagent type: linker
• grupo funcional: azide; fluoro; sulfinic acid
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: [Na+].[O-]S(=O)C(F)(F)CCCCCCN=[N+]=[N-]
• InChI: 1S/C7H13F2N3O2S.Na/c8-7(9,15(13)14)5-3-1-2-4-6-11-12-10;/h1-6H2,(H,13,14);/q;+1/p-1
• chave InChI: FFNHIEJQAMGBCZ-UHFFFAOYSA-M

Descrição

Aplicação

Within heteroarene platforms, DAAS-Na allows for the direct introduction of a difluoroalkyl chain carrying an azide group, which is designed for the purpose of bioconjugation. Through a Huisgen cycloaddition (a "click" reaction), the azide moiety can then be reacted with a terminal alkyne that is bound to a functional molecule such as biomacromolecules. This effectively allows for a covalent linkage between a heteroarene and any target molecule, for example, between a heteroarene-containing drug and an antibody. This reagent was developed by the Baran Group and is one of several reagents for the direct alkylation of heterocycles.

Learn More at the Professor and Product Portal of Professor Phil S. Baran.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H315,H319,H335
• Declarações de precaução: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classificações de perigo: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable