699918

(R)-N-[(1R,2R)-2-(3-(3,5-Bis(trifluoromethyl)phenyl)ureido)cyclohexyl]-tert-butyl-sulfinamide

96%

• Sinônimo(s): [S(R)]-N-[(1R,2R)-2-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]carbonyl]amino]cyclohexyl]-2-methyl-2-propanesulfinamide
• Fórmula empírica (Notação de Hill): C₁₉H₂₅F₆N₃O₂S
• Número CAS: 934762-68-2
• Peso molecular: 473.48
• Número MDL: MFCD11656068
• Código UNSPSC: 12352002
• ID de substância PubChem: 329762164
• NACRES: NA.22

Propriedades

• Nível de qualidade: 100
• Ensaio: 96%
• Formulário: solid
• pf: 173-181 °C
• grupo funcional: amine; fluoro
• cadeia de caracteres SMILES: CC(C)(C)S(=O)N[C@@H]1CCCC[C@H]1NC(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F
• InChI: 1S/C19H25F6N3O2S/c1-17(2,3)31(30)28-15-7-5-4-6-14(15)27-16(29)26-13-9-11(18(20,21)22)8-12(10-13)19(23,24)25/h8-10,14-15,28H,4-7H2,1-3H3,(H2,26,27,29)/t14-,15-,31-/m1/s1
• chave InChI: WMIJNZVQFOPOBW-ZHANGXNJSA-N

Descrição

Aplicação

(R)-N-[(1R,2R)-2-(3-(3,5-Bis(trifluoromethyl)phenyl)ureido)cyclohexyl]-tert-butyl-sulfinamide is a sulfinamide-urea based chiral catalyst that can be used to synthesize:

• Enantioselective homoallylic amines by asymmetric allylation of acylhydrazones with allylindium reagents.
• Tetrahydroquinolines via an asymmetric Povarov reaction.
• 2-aryl-substituted cycloalkanones by enantioselective protonation of corresponding trimethylsilyl enol ethers.

Informações de segurança

• Frases de perigo: H413
• Classificações de perigo: Aquatic Chronic 4
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)