688495

(S)-4-tert-Butyl-2-[2-(diphenylphosphino)phenyl]-2-oxazoline

97%

• Sinônimo(s): (4S)-tert-Butyl-2-[2-(diphenylphosphino)phenyl]-4,5-dihydrooxazole
• Fórmula empírica (Notação de Hill): C₂₅H₂₆NOP
• Número CAS: 148461-16-9
• Peso molecular: 387.45
• Número MDL: MFCD09998277
• Código UNSPSC: 12352005
• ID de substância PubChem: 329761168
• NACRES: NA.22

Propriedades

• Nível de qualidade: 100
• Ensaio: 97%
• forma: solid
• atividade óptica: [α]22/D -57.0°, c = 1 in chloroform
• pf: 111-116 °C
• grupo funcional: ether; phosphine
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: CC(C)(C)[C@@H]1N=C(C2=CC=CC=C2P(C3=CC=CC=C3)C4=CC=CC=C4)OC1
• InChI: 1S/C25H26NOP/c1-25(2,3)23-18-27-24(26-23)21-16-10-11-17-22(21)28(19-12-6-4-7-13-19)20-14-8-5-9-15-20/h4-17,23H,18H2,1-3H3/t23-/m1/s1
• chave InChI: DMOLTNKQLUAXPI-HSZRJFAPSA-N

Descrição

Descrição geral

The product is a phosphinooxazoline (PHOX) ligand introduced by Pfaltz and coworkers. These non-symmetrical modular P,N-ligands are particularly useful in cases where double bond migration leads to undesired products or mixtures of isomers.

Aplicação

(S)-4-tert-Butyl-2-[2-(diphenylphosphino)phenyl]-2-oxazoline can be used as a ligand for enantioselective Heck reaction without any C=C double bond migration byproduct. It can also be used in a rhodium(I)-catalyzed enantioselective desymmetrization reaction of meso-3,5-dimethyl glutaric anhydride, to form substituted syn-deoxypolypropionate fragments in a single transformation.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)