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53695

Sigma-Aldrich

3-(Tritylthio)propionic acid

≥97.0% (T)

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About This Item

Fórmula linear:
(C6H5)3CSCH2CH2COOH
Número CAS:
27144-18-9
Peso molecular:
348.46
Número MDL:
MFCD00237291
Código UNSPSC:
12352100
ID de substância PubChem:
57651432
NACRES:
NA.22

Nível de qualidade

100

Ensaio

≥97.0% (T)

grupo funcional

carboxylic acid
phenyl
thioether

cadeia de caracteres SMILES

OC(=O)CCSC(c1ccccc1)(c2ccccc2)c3ccccc3

InChI

1S/C22H20O2S/c23-21(24)16-17-25-22(18-10-4-1-5-11-18,19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15H,16-17H2,(H,23,24)

chave InChI

AECGEIVNZGQBJT-UHFFFAOYSA-N

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H302,H315,H319,H335,H413

Classificações de perigo

Acute Tox. 4 Oral - Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análise (COA)

Lot/Batch Number
BCBP8287V
BCBJ8354V
BCBG7017V
1439717V
1421618V

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Fmoc-Tyr(tBu)-OH ≥98.0% (HPLC)

Sigma-Aldrich

47623

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Sigma-Aldrich

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Mathew R Schnorenberg et al.
ACS omega, 3(10), 14144-14150 (2018-11-10)
Despite the therapeutic promise of phospholipid-based nanocarriers, a major obstacle to their widespread clinical translation is a susceptibility to fatty acid ester hydrolysis, leading to lack of quality control and inconsistencies in self-assembly formulations. Using electrospray ionization mass spectrometry fragmentation
Naglaa Salem El-Sayed et al.
Molecules (Basel, Switzerland), 24(7) (2019-04-14)
Cell-penetrating peptide [WR]₅ has been previously shown to be an efficient molecular transporter for various hydrophilic and hydrophobic molecules. The peptide was synthesized using Fmoc/tBu solid-phase chemistry, and one arginine was replaced with one lysine to enable the conjugation with
Partha Laskar et al.
Nanoscale, 11(42), 20058-20071 (2019-10-16)
Combination therapy involving chemotherapeutic drugs and genes is emerging as a promising strategy to provide a synergistic therapeutic effect, to overcome drug resistance while reducing the severe side effects associated with conventional chemotherapeutic drugs. However, the lack of nanomedicines able
Scott H Medina et al.
Journal of controlled release : official journal of the Controlled Release Society, 209, 317-326 (2015-05-17)
Many lead molecules identified in drug discovery campaigns are eliminated from consideration due to poor solubility and low cell permeability. These orphaned molecules could have clinical value if solubilized and delivered properly. SVS-1 is a de novo designed peptide that

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