Pular para o conteúdo
Merck
Todas as fotos(4)

Documentos Principais

Visualizar Toda a Documentação

408719

Sigma-Aldrich

Polyethylenimine, branched

average Mw ~800 by LS, average Mn ~600 by GPC

Sinônimo(s):

PEI, ethylenediamine branched

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(4)

About This Item

Fórmula linear:
H(NHCH2CH2)nNH2
Número CAS:
25987-06-8
Número MDL:
MFCD00084427
Código UNSPSC:
12162002
NACRES:
NA.23

Formulário

viscous liquid

Nível de qualidade

200

peso molecular

average Mn ~600 by GPC
average Mw ~800 by LS

índice de refração

n20/D 1.5240

densidade

1.050 g/mL at 25 °C

cadeia de caracteres SMILES

N1CC1.NCCN

InChI

1S/C2H8N2.C2H5N/c3-1-2-4;1-2-3-1/h1-4H2;3H,1-2H2

chave InChI

SFLOAOINZSFFAE-UHFFFAOYSA-N

Categorias relacionadas

Descrição geral

Polyethyleneimine is a hydrophilic polymerwidely used as a non-viral synthetic vector for invivo delivery of therapeutic nucleic acids. Owing to its excellentphysicochemical properties, it is applied in many fields like the separationand purification of proteins, carbon dioxide absorption, drug carriers,effluent treatment, and biological labels.

Aplicação

Branched PEI can be used as a precursor to synthesize conjugated polyplexes for efficient gene transfection. Conjugation of PEI with Jeffamine polyether and guanidinylation of the amino groups of PEI reduce the cytotoxicity of the polyplexes and protect them from aggregation in the presence of serum proteins.

Bamboo charcoal impregnated with PEI can be used as a CO2 adsorbent. Numerous amino groups present in PEI can react with CO2 due to acid-alkali interaction and enhance the adsorption capacity of bamboo charcoal.

It can also be used to prepare cross-linked water-soluble polymers with high coordination capabilities towards organic drug molecules.

Características e benefícios

  • Branched PEI has better complexation and buffering capacity.
  • High ion exchange capacity and affinity toward proteins.
  • SignificantDNA transfer efficiency.

forma física

Branched polymer

Palavra indicadora

Danger

Frases de perigo

H302,H318,H411

Classificações de perigo

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

356.0 °F

Ponto de fulgor (°C)

180 °C

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
MKCJ2767
MKCG7251
MKCG3800
MKCG3796
MKCG3795

Não está vendo a versão correta?

Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

Pesquise por COA

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 5

1 of 5

Poly(ethyleneimine) solution ~50% in H2O

Sigma-Aldrich

03880

Poly(ethyleneimine) solution

Poly(ethyleneimine) solution analytical standard, 50 % (w/v) in H2O

Supelco

P3143

Poly(ethyleneimine) solution

Polyethylenimine hydrochloride linear, average Mn 10,000, PDI ≤1.5

Sigma-Aldrich

764647

Polyethylenimine hydrochloride

Polyethylenimine hydrochloride linear, average Mn 4,000, PDI ≤1.3

Sigma-Aldrich

764892

Polyethylenimine hydrochloride

Polyethylenimine on silica gel powder, 40-200 mesh

Sigma-Aldrich

246751

Polyethylenimine on silica gel

Valentina Dinca et al.
Sensors (Basel, Switzerland), 18(12) (2018-12-07)
Developing a controlled method for obtaining hybrid enzymatic-based interfaces for sensing application require the use of a multiuse, reusable sensor. By controlling the interface characteristics in terms of the surface chemistry, thickness, and roughness, a tailored response toward various toxic
Andrew Jajack et al.
PloS one, 14(1), e0210286-e0210286 (2019-01-17)
Insurmountable detection challenges will impede the development of many of the next-generation of lab-on-a-chip devices (e.g., point-of-care and real-time health monitors). Here we present the first membrane-based, microfluidic sample preconcentration method that is continuous, quantifiable, simple, and capable of working
Anna Alhaddad et al.
PloS one, 7(12), e52207-e52207 (2013-01-04)
Small interfering RNAs (siRNAs) are powerful tools commonly used for the specific inhibition of gene expression. However, vectorization is required to facilitate cell penetration and to prevent siRNA degradation by nucleases. We have shown that diamond nanocrystals coated with cationic

Artigos

Functionalized PEI and Its Role in Gene Therapy
Nanoparticle-Based Drug and Gene Delivery for Tumor Targeting

Professor Yoshiki Katayama (Kyushu University, Japan) discusses recent advances in drug delivery systems and strategies that exploit the EPR effect, with a special focus on stimuli-responsive systems based on novel materials.

Polyelectrolyte Multilayer Films and Membrane Functionalization

We present an article that discusses two applications in particular; first, using these layers as polyelectrolyte membranes to control permeability.

Global Trade Item Number

SKUGTIN
408719-100ML4061838253675
408719-1L4061831988703
408719-250ML4061831988710

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica