Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos Principais

Visualizar Toda a Documentação

765090

Sigma-Aldrich

Polyethylenimine, linear

average Mn 10,000, PDI ≤1.3

Sinônimo(s):

PEI

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(1)

About This Item

Fórmula linear:
(CH2CH2NH)n
Número CAS:
9002-98-6
Número MDL:
MFCD00039669
Código UNSPSC:
12162002
NACRES:
NA.23

Formulário

solid

Nível de qualidade

100

peso molecular

average Mn 10,000

pf

48-53 °C

PDI

≤1.3

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

N1CC1

InChI

1S/C2H5N/c1-2-3-1/h3H,1-2H2

chave InChI

NOWKCMXCCJGMRR-UHFFFAOYSA-N

Procurando produtos similares? Visita Guia de comparação de produtos

Categorias relacionadas

Descrição geral

Polyethylenimine (linear) is a versatile cationic polymer with a high transfection efficiency. It is used as a gene delivery reagent. It is a non-lipid polycation that can be used to transfect oligonucleotides and plasmid into cells in vitro and in vivo.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315,H319

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
MKCH4846
MKCF0987
MKCC1827
MKBV9404V
MKBR2633V

Não está vendo a versão correta?

Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

Pesquise por COA

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 6

1 of 6

Poly(ethyleneimine) solution ~50% in H2O

Sigma-Aldrich

03880

Poly(ethyleneimine) solution

Poly(ethyleneimine) solution average Mn ~1,200, average Mw ~1300 by LS, 50 wt. % in H2O

Sigma-Aldrich

482595

Poly(ethyleneimine) solution

Branched PEI-g-PEG PEG Mn 5,000

Sigma-Aldrich

900743

Branched PEI-g-PEG

Polyethylenimine, 80% ethoxylated solution 37 wt. % in H2O

Sigma-Aldrich

306185

Polyethylenimine, 80% ethoxylated solution

Branched PEI-g-PEG PEG Mn 550

Sigma-Aldrich

900926

Branched PEI-g-PEG

Poly(2-ethyl-2-oxazoline) average Mn 20,000, PDI <1.4

Sigma-Aldrich

741884

Poly(2-ethyl-2-oxazoline)

Bromodomain and extra-terminal (BET) protein inhibitors suppress chondrocyte differentiation and restrain bone growth
Niu N, et al.
The Journal of biological chemistry, 291(52), 26647-26657 (2016)
Systemic linear polyethylenimine (L-PEI)-mediated gene delivery in the mouse
Zou S, et al.
The journal of gene medicine, 2(2), 128-134 (2000)
A comparison of linear and branched polyethylenimine (PEI) with DCChol/DOPE liposomes for gene delivery to epithelial cells in vitro and in vivo
Wiseman JW, et al.
Gene Therapy, 10(19), 1654-1654 (2003)
Marie-Elise Bonnet et al.
Pharmaceutical research, 25(12), 2972-2982 (2008-08-19)
The success of nucleic acid therapies depends upon delivery vehicle's ability to selectively and efficiently deliver therapeutic nucleic acids to target organ with minimal toxicity. The cationic polymer polyethylenimine (PEI) has been widely used for nucleic acid delivery due to
Dae Hee Lee et al.
Biomaterials, 171, 34-45 (2018-04-22)
Limitation of current anti-Vascular Endothelial Growth Factor (VEGF) cancer therapy is transitory responses, inevitable relapses and its insufficient tumor-targeting. Thus, multifaceted approaches, including the development of bispecific antibodies and combination strategies targeting different pathways have been proposed as an alternative.
Exibir todos os documentos relacionados

Artigos

Delivery of Nucleic Acids Using Polymers

Delivery of Nucleic Acids Using Polymers

Functionalized PEI and Its Role in Gene Therapy
Nanoparticle-Based Drug and Gene Delivery for Tumor Targeting

Professor Yoshiki Katayama (Kyushu University, Japan) discusses recent advances in drug delivery systems and strategies that exploit the EPR effect, with a special focus on stimuli-responsive systems based on novel materials.

Functional Polymers for Biomedical Applications

Wide range of functional polymers for biomedical applications have been synthesized and structurally characterized. Several classes of polymers including biodegradable polymers, hydrophilic & amphiphilic polymers, and stimuli responsive polymers have been prepared using controlled and directed functionalization via "living" polymerization such as RAFT, ionic and ring opening polymerization. Selected polymers have been studied for their structure-properties relationship. "

Global Trade Item Number

SKUGTIN
765090-1G4061835508716

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica