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764604

Sigma-Aldrich

Polyethylenimine, linear

average Mn 2100, PDI <1.3

Sinônimo(s):

PEI

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About This Item

Fórmula linear:
(CH2CH2NH)n
Número CAS:
9002-98-6
Número MDL:
MFCD00039669
Código UNSPSC:
12162002
NACRES:
NA.23

Formulário

liquid

peso molecular

average Mn 2100

pf

59-64 °C

temperatura de transição

Tm 59-64 °C

PDI

<1.3

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

N1CC1

InChI

1S/C2H5N/c1-2-3-1/h3H,1-2H2

chave InChI

NOWKCMXCCJGMRR-UHFFFAOYSA-N

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Descrição geral

Polyethylenimine(PEI) is a synthetic cationic polymerwith high charge density and chain flexibility. It is the most widelyinvestigated cationic polymer for non-viral delivery of nucleic acids. LinearPEI can be an effective carrier for a wide range of gene medicine including DNAplasmids, small interfering RNAs, and mRNAs. It protects the DNA from theacidic environment and ensures the release of DNA to the cytoplasm.

Aplicação

  • Water-soluble linear poly (ethylenimine) as a superior bifunctional binder for lithium–sulfur batteries: Demonstrates the utility of water-soluble linear polyethylenimine as an effective bifunctional binder that enhances the cycle stability and efficiency of lithium-sulfur batteries, pivotal for advancing battery technology (Liao et al., 2018).

Palavra indicadora

Danger

Frases de perigo

H302,H317,H318,H411

Classificações de perigo

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number
MKCM1906
MKCF6816
MKBX2662V
MKBT6089V
MKBS2119V

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Lei Feng et al.
Engineering in life sciences, 20(8), 320-330 (2020-08-11)
As the main immunogen that could stimulate neutralized antibody in pigs, recombinant E2 protein of CSFV was expressed in CHO-dhfr-cells driven by endogenous Txnip promoter from Chinese hamster. Different fragments of Txnip promoter were amplified by PCR from isolated genomic
Laura R H Ip et al.
Oncotarget, 6(12), 10548-10562 (2015-04-15)
Treatment options for ovarian cancer patients remain limited and overall survival is less than 50% despite recent clinical advances. The lipid phosphatase inositol polyphosphate 4-phosphatase type II (INPP4B) has been described as a tumor suppressor in the PI3K/Akt pathway with

Artigos

Delivery of Nucleic Acids Using Polymers

Delivery of Nucleic Acids Using Polymers

Functionalized PEI and Its Role in Gene Therapy
Nanoparticle-Based Drug and Gene Delivery for Tumor Targeting

Professor Yoshiki Katayama (Kyushu University, Japan) discusses recent advances in drug delivery systems and strategies that exploit the EPR effect, with a special focus on stimuli-responsive systems based on novel materials.

Functional Polymers for Biomedical Applications

Wide range of functional polymers for biomedical applications have been synthesized and structurally characterized. Several classes of polymers including biodegradable polymers, hydrophilic & amphiphilic polymers, and stimuli responsive polymers have been prepared using controlled and directed functionalization via "living" polymerization such as RAFT, ionic and ring opening polymerization. Selected polymers have been studied for their structure-properties relationship. "

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