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198250

Sigma-Aldrich

Rose bengal

certified by the Biological Stain Commission, Dye content ≥80 %

Sinônimo(s):

4,5,6,7-Tetrachloro-2′,4′,5′,7′-tetraiodofluorescein disodium salt, Acid Red 94, Bengal Rose B sodium salt, Rose Bengal sodium salt

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About This Item

Fórmula empírica (Notação de Hill):
C20H2Cl4I4Na2O5
Número CAS:
632-69-9
Peso molecular:
1017.64
Número do índice de cores:
45440
Beilstein:
3645857
Número CE:
211-183-3
Número MDL:
MFCD00005043
Código UNSPSC:
12171500
ID de substância PubChem:
24851870
NACRES:
NA.47

grau

certified by the Biological Stain Commission

Nível de qualidade

100

forma

powder

composição

Dye content, ≥80%

cor

dark violet

solubilidade

H2O: 1 mg/mL

λmax

548 nm

ε (coeficiente de extinção)

≥90000 at 546-550 nm at 0.008 g/L

aplicação(ões)

diagnostic assay manufacturing
hematology
histology

temperatura de armazenamento

room temp

cadeia de caracteres SMILES

[Na+].[Na+].[O-]C(=O)c1c(Cl)c(Cl)c(Cl)c(Cl)c1C2=C3C=C(I)C(=O)C(I)=C3Oc4c(I)c([O-])c(I)cc24

InChI

1S/C20H4Cl4I4O5.2Na/c21-10-8(9(20(31)32)11(22)13(24)12(10)23)7-3-1-5(25)16(29)14(27)18(3)33-19-4(7)2-6(26)17(30)15(19)28;;/h1-2,29H,(H,31,32);;/q;2*+1/p-2

chave InChI

UWBXIFCTIZXXLS-UHFFFAOYSA-L

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Descrição geral

Rose Bengal is the sodium salt of tetraiodotetrachlorouorescein, C20H2O5I4Cl4Na2. It is an anionic water-soluble xanthene dye.

Aplicação

Rose bengal has several microbilogical staining applications including:
  • Conn′s technique for bacteria in soil and Kreyberg′s stain for keratin and mucus
  • counterstaining hematoxylin
  • staining cellular inclusions, together with Bismark brown



Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Certificados de análise (COA)

Lot/Batch Number
SHBN9281
SHBN7446
SHBN2859
SHBM7411
SHBM4755

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Azul de metileno certified by the Biological Stain Commission

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Azul de metileno

Steffanie Heindl et al.
The Journal of experimental medicine, 218(8) (2021-05-27)
Neuroinflammation is an emerging focus of translational stroke research. Preclinical studies have demonstrated a critical role for brain-invading lymphocytes in post-stroke pathophysiology. Reducing cerebral lymphocyte invasion by anti-CD49d antibodies consistently improves outcome in the acute phase after experimental stroke models.
J Varga et al.
Studies in mycology, 69(1), 1-17 (2011-09-06)
Four new species, Aspergillus eucalypticola, A. neoniger, A. fijiensis and A. indologenus are described and illustrated. Aspergillus eucalypticola was isolated from Eucalyptus leaf from Australia, and is related to A. tubingensis and A. costaricaensis, but could clearly be distinguished from
Rebecca Sadler et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(5), 1162-1173 (2020-01-01)
Recovery after stroke is a multicellular process encompassing neurons, resident immune cells, and brain-invading cells. Stroke alters the gut microbiome, which in turn has considerable impact on stroke outcome. However, the mechanisms underlying gut-brain interaction and implications for long-term recovery
Y Hiasa et al.
Japanese journal of cancer research : Gann, 79(3), 314-319 (1988-03-01)
The effects of erythrosine (Red 3), rose bengal B (Red 105) and thyroidectomy on the development of thyroid tumor were examined in male Wistar rats treated with N-bis(2-hydroxypropyl)nitrosamine (DHPN). Red 3 and Red 105 were used at 4% in the
A Ito et al.
Journal of the National Cancer Institute, 77(1), 277-281 (1986-07-01)
The tumorigenicity of 9-3',4',5',6'-tetrachloro-o-carboxy phenyl-6-hydroxy-2,4,5,7-tetraiodo-3-isoxanthone sodium (CAS: 632-68-8) [also called Food Red 105 (FR 105) or Rose Bengal B], which is widely used for food or cosmetic coloring in Japan, was examined in (C57BL/6N X C3H/N)F1 mice. Animals were divided
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