142077

2,2,2-Trichloroethyl chloroformate

98%

• Sinônimo(s): 2,2,2-Trichloroethoxycarbonyl chloride
• Fórmula linear: ClCOOCH₂CCl₃
• Número CAS: 17341-93-4
• Peso molecular: 211.86
• Beilstein: 970619
• Número CE: 241-363-7
• Número MDL: MFCD00000810
• Código UNSPSC: 12352100
• ID de substância PubChem: 24848380
• NACRES: NA.22

Propriedades

• pressão de vapor: 0.06 psi ( 20 °C)
• Nível de qualidade: 200
• Ensaio: 98%
• forma: liquid
• índice de refração: n20/D 1.471 (lit.)
• pb: 171-172 °C (lit.)
• densidade: 1.539 g/mL at 25 °C (lit.)
• grupo funcional: chloro
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: ClC(=O)OCC(Cl)(Cl)Cl
• InChI: 1S/C3H2Cl4O2/c4-2(8)9-1-3(5,6)7/h1H2
• chave InChI: LJCZNYWLQZZIOS-UHFFFAOYSA-N

Descrição

Descrição geral

2,2,2-Trichloroethyl chloroformate (TrocCl) serves as a versatile reagent used for selective acylation and dealkylation in organic synthesis. It is used in regio, chemo, and stereoselective synthesis.

Aplicação

• 2,2,2-Trichloroethyl chloroformate was used as derivatizing reagent in gas chromatographic/mass spectrometric determination of a large range of amphetamine-related drugs and ephedrines in plasma, urine and hair samples.
• It was used as starting reagent during the synthesis of 6-Nor-9,10-dihydrolysergic acid methyl ester.
• It was used as reagent during N-demethylation of dextromethorphan.
• It was used as protecting reagent for aliphatic and aromatic hydroxyl and amino groups.

Protecting reagent for aliphatic and aromatic hydroxyl and amino groups.

Informações de segurança

• Pictogramas: GHS06,GHS05
• Palavra indicadora: Danger
• Frases de perigo: H314,H331
• Declarações de precaução: P280 - P303 + P361 + P353 - P304 + P340 + P311 - P305 + P351 + P338 + P310
• Classificações de perigo: Acute Tox. 3 Inhalation - Eye Dam. 1 - Skin Corr. 1B
• Código de classe de armazenamento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter