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Key Documents

139912

Sigma-Aldrich

Phytol

95%, mixture of isomers

Sinônimo(s):

3,7,11,15-Tetramethyl-2-hexadecen-1-ol

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About This Item

Fórmula linear:
CH3[CH(CH3)(CH2)3]3C(CH3)=CHCH2OH
Número CAS:
Peso molecular:
296.53
Beilstein:
1726098
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de substância PubChem:
NACRES:
NA.22

Nível de qualidade

Ensaio

95%

forma

(Liquid or Viscous Liquid)

índice de refração

n20/D 1.463 (lit.)

pb

202-204 °C/10 mmHg (lit.)

densidade

0.85 g/mL at 25 °C (lit.)

grupo funcional

hydroxyl

cadeia de caracteres SMILES

CC(C)CCCC(C)CCCC(C)CCC\C(C)=C\CO

InChI

1S/C20H40O/c1-17(2)9-6-10-18(3)11-7-12-19(4)13-8-14-20(5)15-16-21/h15,17-19,21H,6-14,16H2,1-5H3/b20-15+

chave InChI

BOTWFXYSPFMFNR-HMMYKYKNSA-N

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Descrição geral

Phytol is a diterpene alcohol and is widely used as a food additive and in medicinal field. It undergoes Mitsunobu reaction with 5-fluorouridine to yield the nucleoterpenes.

Aplicação

Phytol was used to investigate the electroantennogram response of males and females of the potato tuber moth, Phthorimaea operculella to various plant volatiles. It was used in the synthesis of pristanic acid (2,6,10,14-tetramethylpentadecanoic acid).

Ações bioquímicas/fisiológicas

Phytol exhibits potential anti-Schistosomal properties. It induces sedative and anxiolytic-like effects in mice.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Declarações de precaução

Classificações de perigo

Aquatic Chronic 4 - Skin Irrit. 2

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

368.6 °F

Ponto de fulgor (°C)

187 °C

Equipamento de proteção individual

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Jéssica Pereira Costa et al.
Brain research, 1547, 34-42 (2013-12-18)
Phytol, a branched chain unsaturated alcohol, is particularly interesting because it is an isolated compound from essential oils of different medicinal plants. The aim of this study was to evaluate the anxiolytic-like effects of phytol in animal models to clarify
P P Van Veldhoven et al.
The Journal of biological chemistry, 266(36), 24676-24683 (1991-12-25)
Isoprenoid (branched) fatty acids such as pristanic acid can be degraded via beta-oxidation in peroxisomes. We synthesized 2-methylpalmitoyl-CoA as a model substrate in order to study the first step of the peroxisomal beta-oxidation of branched fatty acids, catalyzed by an
Edith Malecki et al.
Chemistry & biodiversity, 10(12), 2209-2220 (2013-12-12)
The cancerostatic 5-fluorouridine (5-FUrd; 1) was sequentially sugar-protected by introduction of a 2',3'-O-heptylidene ketal group (→2), followed by 5'-O-monomethoxytritylation (→3). This fully protected derivative was submitted to Mitsunobu reactions with either phytol ((Z and E)-isomer) or nerol ((Z)-isomer) to yield
P D Das et al.
Journal of biosciences, 32(2), 339-349 (2007-04-17)
Electroantennograms (EAGs)were recorded from males and females of the potato tuber moth,Phthorimaea operculella in response to a broad range of plant volatile compounds belonging to diverse chemical classes.The responses to 27 compounds were evaluated,which indicated significant differences in EAGs between
Josué de Moraes et al.
PLoS neglected tropical diseases, 8(1), e2617-e2617 (2014-01-07)
Schistosomiasis is a major endemic disease that affects hundreds of millions worldwide. Since the treatment and control of this parasitic disease rely on a single drug, praziquantel, it is imperative that new effective drugs are developed. Here, we report that

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