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Documentos Principais

130001

Sigma-Aldrich

1-Methylpiperazine

99%

Sinônimo(s):

N-Methylpiperazine

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About This Item

Fórmula empírica (Notação de Hill):
C5H12N2
Número CAS:
Peso molecular:
100.16
Beilstein:
102724
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de substância PubChem:
NACRES:
NA.22

densidade de vapor

3.5 (vs air)

Nível de qualidade

Ensaio

99%

Formulário

liquid

índice de refração

n20/D 1.466 (lit.)

p.e.

138 °C (lit.)

densidade

0.903 g/mL at 25 °C (lit.)

cadeia de caracteres SMILES

CN1CCNCC1

InChI

1S/C5H12N2/c1-7-4-2-6-3-5-7/h6H,2-5H2,1H3

chave InChI

PVOAHINGSUIXLS-UHFFFAOYSA-N

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Descrição geral

1-Methylpiperazine is a heterocyclic diamine used as a versatile building block and intermediate in organic synthesis.

Aplicação

1-Methylpiperazine was used as mimic template in the preparation of molecularly imprinted microspheres (MIMs). It was also used to prepare the difunctional strong anion-exchange stationary phase from a 1,4-diazacyclohexane derivative.

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - Skin Sens. 1B

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

88.7 °F - closed cup

Ponto de fulgor (°C)

31.5 °C - closed cup

Equipamento de proteção individual

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Slide 1 of 5

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Juxiang Ruan et al.
Journal of chromatography. A, 1297, 77-84 (2013-06-01)
This paper reports the preparation of a novel, silica-based, strong anion-exchange stationary phase from a 1,4-diazacyclohexane derivative. To prepare the difunctional strong anion-exchange stationary phase, activated silica beads were first bonded with 3-chloropropyltriethoxysilane and then reacted with 1-methylpiperazine followed by
Hongyuan Yan et al.
The Analyst, 137(12), 2884-2890 (2012-05-04)
A highly selective molecularly imprinted solid-phase extraction (MISPE) combined with liquid chromatography-ultraviolet detection was developed for the simultaneous isolation and determination of four plant hormones including indole-3-acetic acid (IAA), indole-3-propionic acid (IPA), indole-3-butyric acid (IBA) and 1-naphthaleneacetic acid (NAA) in
H Welinder et al.
International archives of allergy and applied immunology, 79(3), 259-262 (1986-01-01)
The presence of specific IgE antibodies against conjugates between human serum albumin and piperazine, a compound previously known to cause occupational asthma, and N-methyl-piperazine, respectively, was demonstrated by RAST, RAST inhibition and skin prick tests in 2 asthmatic subjects occupationally
A R Roudman et al.
Journal of biomedical materials research, 39(4), 667-672 (1998-03-10)
Aminated poly(vinyl chloride) (PVC) membranes were prepared that had a Nernstian response over a wide range of pH. The reaction between PVC and methyl-piperazine (MePIP) in dimethylformamide (DMF) was studied over a wide range of time and temperature, and in
S A Leach et al.
Carcinogenesis, 8(12), 1907-1912 (1987-12-01)
Human exposure to endogenously formed N-nitroso compounds has frequently been suggested as a causative factor in carcinogenesis where this is related to chronic bacterial infection such as is seen in gastric achlorhydria. At least two distinct mechanisms of endogenous formation

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