ESRRG
estrogen-related receptor gamma
Sinônimos:
ERR3, ERRgamma, NR3B3
Espécies:
Human ESRRG (2104), Mouse Esrrg (26381), Rat Esrrg (360896), chicken ESRRG (421357), Horse ESRRG (100050530), cow ESRRG (536732), domestic cat ESRRG (101091751), dog ESRRG (478961), sheep ESRRG (101102323), domestic guinea pig Esrrg (100719060)
ID UniProtKB:
ID do gene:
- Human(2104) Summary: This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, modulates cell proliferation and estrogen signaling in breast cancer, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation. Multiple alternatively spliced transcript variants have been identified, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region. [provided by RefSeq, Aug 2011]
- Mouse(26381) estrogen-related receptor gamma
- Rat(360896) estrogen-related receptor gamma
- chicken(421357) estrogen-related receptor gamma
- Horse(100050530) estrogen-related receptor gamma
- cow(536732) estrogen-related receptor gamma
- domestic cat(101091751) estrogen-related receptor gamma
- dog(478961) estrogen-related receptor gamma
- sheep(101102323) estrogen-related receptor gamma
- domestic guinea pig(100719060) estrogen-related receptor gamma
- naked mole-rat(101705764) estrogen-related receptor gamma
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Antagonist
Número do produto
Descrição
Espécies
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-ESRRG antibody produced in rabbit, IgG fraction of antiserum,
Reatividade de espécies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicação
immunohistochemistry
western blot
western blot
Anti-ESRRG antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicação
western blot
Anti-ESRRG antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
bovine, dog, hamster, horse, human, monkey, mouse, rabbit, rat
Aplicação
ELISA
immunohistochemistry
immunohistochemistry
Anti-ESRRG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-ESRRG Antibody, clone 2W3A9, Rabbit Monoclonal, ,
Reatividade de espécies
human, rat
Aplicação
western blot