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Merck

Y0001099

Valaciclovir Unreinheit G

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

4-(Dimethylamino)-pyridin, N,N-Dimethylpyridin-4-amin, DMAP

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About This Item

Empirische Formel (Hill-System):
C7H10N2
CAS-Nummer:
Molekulargewicht:
122.17
Beilstein:
110354
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

valacyclovir

Hersteller/Markenname

EDQM

mp (Schmelzpunkt)

108-110 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

CN(C)c1ccncc1

InChI

1S/C7H10N2/c1-9(2)7-3-5-8-6-4-7/h3-6H,1-2H3

InChIKey

VHYFNPMBLIVWCW-UHFFFAOYSA-N

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Allgemeine Beschreibung

4-(Dimethylamino)pyridine (DMAP) is an excellent catalyst for acylation of hindered alcohols and in chemical transformations. It is highly nucleophilic in nature.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Ein hocheffizienter Katalysator für Acylierungsreaktionen

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 1

Zielorgane

Nervous system

Lagerklassenschlüssel

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flammpunkt (°F)

255.2 °F

Flammpunkt (°C)

124 °C


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Analysenzertifikate (COA)

Lot/Batch Number

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Configurationally Stable Biaryl Analogues of 4-(Dimethylamino) pyridine: A Novel Class of Chiral Nucleophilic Catalysts.
Spivey, Alan C., et al.
The Journal of Organic Chemistry, 64.26, 9430-9443 (1999)
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Taxanes are a class of anticancer agents with a broad spectrum and have been widely used to treat a variety of cancer. However, its long-term use has been hampered by accumulating toxicity and development of drug resistance. The most extensively
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Journal of chromatography. A, 1386, 53-61 (2015-02-18)
Increasing evidence suggests that phospholipid peroxidation plays important roles in the pathogenesis of various diseases, such as atherosclerosis. With regard to the biochemical processes that initiate phospholipid peroxidation in vivo, enzymatic conversion of phosphatidylcholine to phosphatidylcholine hydroperoxide (PCOOH) by lipoxygenase

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