PHR1218

trans-Anethol

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(e): 4-Propenylanisol, trans-1-Methoxy-4-propenyl-benzol
• Lineare Formel: CH₃CH=CHC₆H₄OCH₃
• CAS-Nummer: 4180-23-8
• Molekulargewicht: 148.20
• Beilstein: 774229
• EG-Nummer: 224-052-0
• MDL-Nummer: MFCD00009284
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329823225
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material; pharmaceutical secondary standard
• Qualitätsniveau: 300
• Agentur: traceable to USP 1035005
• API-Familie: anethole
• Analysenzertifikat (CofA): current certificate can be downloaded
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Brechungsindex: n20/D 1.561 (lit.)
• bp: 234-237 °C (lit.)
• mp (Schmelzpunkt): 20-21 °C (lit.)
• Dichte: 0.988 g/mL at 25 °C (lit.)
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-30°C
• SMILES String: COc1ccc(\C=C\C)cc1
• InChI: 1S/C10H12O/c1-3-4-9-5-7-10(11-2)8-6-9/h3-8H,1-2H3/b4-3+
• InChIKey: RUVINXPYWBROJD-ONEGZZNKSA-N

Beschreibung

Allgemeine Beschreibung

trans-Anethole is an aromatic monoterpenoid compound and derivative of phenylpropene. It is predominantly used as a fragrance in cosmetics and as a flavoring agent in food and pharmaceutical industries.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Anwendung

trans-Anethole may be used as an analytical reference standard for the determination of the analyte in raw material, food products and pharmaceutical formulations by high performance liquid chromatography and gas chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem./physiol. Wirkung

Natürlich vorkommendes Phenylpropen-Derivat das in geringerer Konzentration Estrogen und in höherer Konzentration zytotoxisch auf Krebszellenlinien wirkt. Die Cytotoxizität beruht auf dem Metabolismus des trans-Anethol zu 4-Hydroxy-1-propenylbenzol.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Sonstige Hinweise

This compound is commonly found in plants of the genus: pimpinella

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAC3326 in the slot below. This is an example certificate only and may not be the lot that you receive.

Sicherheitshinweise

• Piktogramme: GHS07,GHS09
• Signalwort: Warning
• H-Sätze: H317,H411
• P-Sätze: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Gefahreneinstufungen: Aquatic Chronic 2 - Skin Sens. 1
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2
• Flammpunkt (°F): 213.8 °F
• Flammpunkt (°C): 101 °C