437573

N,N-Dimethylformamid

ACS reagent, ≥99.8%

• Synonym(e): DMF, NSC 5356
• Lineare Formel: HCON(CH₃)₂
• CAS-Nummer: 68-12-2
• Molekulargewicht: 73.09
• Beilstein: 605365
• EG-Nummer: 200-679-5
• MDL-Nummer: MFCD00003284
• UNSPSC-Code: 12352111
• PubChem Substanz-ID: 24867382

Eigenschaften

• Qualität: ACS reagent
• Qualitätsniveau: 200
• Dampfdichte: 2.5 (vs air)
• Dampfdruck: 2.7 mmHg ( 20 °C)
• Assay: ≥99.8%
• Form: liquid
• Selbstzündungstemp.: 833 °F
• Expl.-Gr.: 15.2 %
• Methode(n): electrophoresis: suitable
• Verunreinigungen: ≤0.0005 meq/g Titr. acid; ≤0.003 meq/g Titr. base; ≤0.15% water
• Abdampfrückstand: ≤0.005%
• Farbe: APHA: ≤15
• Brechungsindex: n20/D 1.430 (lit.)
• pH-Wert: 6.7
• bp: 153 °C (lit.)
• mp (Schmelzpunkt): −61 °C (lit.)
• Löslichkeit: water: miscible
• Dichte: 0.944 g/mL (lit.)
• SMILES String: [H]C(=O)N(C)C
• InChI: 1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3
• InChIKey: ZMXDDKWLCZADIW-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

N,N-Dimethylformamide (DMF) is a polar organic solvent with a wide range of industrial applications. It is a precursor for numerous reactions such as formylation, aminocarbonylation, amination, amidation and cyanation. Along with phosphorus oxychloride, it forms Vilsmeier reagent used in the formylation of reactive aromatic and heteroaromatic substrates. Dielectric relaxation experiments on DMF have been conducted between 238.15K and 338.15K. The thermophysical properties of the molecular interactions between DMF and the ionic liquids, ammonium salts and imidazolium salts have been studied. The characteristics of solute-solvent interactions between ammonium nitrate and DMF have been investigated.

Anwendung

N,N-Dimethylformamide (DMF) may be used in the following processes:

• As a solvent synthesis of gold nanoparticles.
• As a solvent in capillary electrophoresis.
• Regioselective synthesis of N,N-dimethylaminopyridzines by reacting with choropyridazines.
• Synthesis of urea-N,N-dimethylformamide, a 3:1 solvate with urea.

Lösungsmittel für viele hydrophobe, organische Verbindungen.

Sicherheitshinweise

• Piktogramme: GHS02,GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H226,H312 + H332,H319,H360D
• P-Sätze: P210 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 2
• Flammpunkt (°F): 135.5 °F - closed cup
• Flammpunkt (°C): 57.5 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter