W381101

Neohesperidin-Dihydrochalkon

≥96%, FG

• Synonym(e): 1-(4-((2-O-[6-Deoxy-α-L-mannopyranosyl]-β-D-glucopyranosyl)-oxy)-2,6-dihydroxyphenyl)-3-[3-hydroxy-4-methoxyphenyl]-1-propanon, NHDC
• Empirische Formel (Hill-System): C₂₈H₃₆O₁₅
• CAS-Nummer: 20702-77-6
• Molekulargewicht: 612.58
• FEMA-Nummer: 3811
• EG-Nummer: 243-978-6
• MDL-Nummer: MFCD00017711
• UNSPSC-Code: 12164502
• PubChem Substanz-ID: 24901889
• Flavis-Nummer: 16.061
• E-Nummer: E 959
• NACRES: NA.21

Eigenschaften

• Biologische Quelle: synthetic
• Qualitätsniveau: 300; 400
• Qualität: FG; Fragrance grade; Halal; Kosher
• Agentur: follows IFRA guidelines
• Einhaltung gesetzlicher Vorschriften: EU Regulation 1223/2009; EU Regulation 1334/2008 & 872/2012
• Assay: ≥96%
• mp (Schmelzpunkt): 156-158 °C (lit.)
• Anwendung(en): flavors and fragrances
• Dokumentation: see Safety & Documentation for available documents
• Nahrungsmittelallergen: no known allergens
• Allergener Duftstoff: no known allergens
• Organoleptisch: odorless
• Lagertemp.: 2-8°C
• SMILES String: COc1ccc(CCC(=O)c2c(O)cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)cc2O)cc1O
• InChI: 1S/C28H36O15/c1-11-21(34)23(36)25(38)27(40-11)43-26-24(37)22(35)19(10-29)42-28(26)41-13-8-16(32)20(17(33)9-13)14(30)5-3-12-4-6-18(39-2)15(31)7-12/h4,6-9,11,19,21-29,31-38H,3,5,10H2,1-2H3/t11-,19+,21-,22+,23+,24-,25+,26+,27-,28+/m0/s1
• InChIKey: ITVGXXMINPYUHD-CUVHLRMHSA-N

Beschreibung

Allgemeine Beschreibung

Neohesperidin dihydrochalcone is mainly used as a sweetener and flavoring agent. It can be prepared by the hydrogenation of neohesperidin, a bitter flavonone found in citrus fruits.

Anwendung

Neohesperidin dihydrochalcone down-regulates MyD88-dependent and -independent signaling by inhibiting endotoxin-induced trafficking of TLR4 to lipid rafts.: This study explores the molecular mechanisms behind the immunomodulatory effects of Neohesperidin dihydrochalcone, revealing its potential to mitigate endotoxin-induced inflammatory responses (Xia et al., 2015).

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• P-Sätze: P264 - P270 - P301 + P312 - P501
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)