ALD01672

N-(1-(benzyloxy)-2-methylpropan-2-yl)-4-(trifluoromethyl)aniline

• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 329772741
• NACRES: NA.22

Eigenschaften

• Form: liquid
• Lagertemp.: 2-8°C
• SMILES String: CC(C)(COCC1=CC=CC=C1)NC2=CC=C(C(F)(F)F)C=C2
• InChI: 1S/C18H20F3NO/c1-17(2,13-23-12-14-6-4-3-5-7-14)22-16-10-8-15(9-11-16)18(19,20)21/h3-11,22H,12-13H2,1-2H3
• InChIKey: JZBFKVSPZMRJGN-UHFFFAOYSA-N

Beschreibung

Anwendung

Traditionally challenging to access, this hindered amine provides a chemically differentiated building block for organic synthesis and medicinal chemistry, specifically for preparation of drug candidates containing hindered amine motifs. Additionally, this and over 80 other sterically hindered secondary amines in the Sigma-Aldrich portfolio provide structurally distinct screening compounds. Screen several through Aldrich Market Select. This hindered amine was accessed via a recent publication reported by Baran and coworkers using an innovative hydroamination method.

Sonstige Hinweise

Product of KemXTree

Practical olefin hydroamination with nitroarenes

Sicherheitshinweise

• Piktogramme: GHS07,GHS09
• Signalwort: Warning
• H-Sätze: H315 - H319 - H410
• P-Sätze: P273 - P280 - P305 + P351 + P338 - P337 + P313 - P391 - P501
• Gefahreneinstufungen: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable