638617

2-(Tri-n-butylstannyl)oxazol

• Synonym(e): 2-(Tributylstannanyl)-1,3-oxazole, 2-(Tributylstannanyl)oxazole, 2-(Tributylstannyl)-1,3-oxazole, 2-(Tributylstannyl)oxazole, Tributyl(oxazol-2-yl)stannane
• Empirische Formel (Hill-System): C₁₅H₂₉NOSn
• CAS-Nummer: 145214-05-7
• Molekulargewicht: 358.11
• MDL-Nummer: MFCD06798076
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 24882955
• NACRES: NA.22

Eigenschaften

• Brechungsindex: n20/D 1.4930 (lit.)
• bp: 108-110 °C/0.2 mmHg (lit.)
• Dichte: 1.170 g/mL at 25 °C; 1.71 g/mL at 25 °C (lit.)
• SMILES String: CCCC[Sn](CCCC)(CCCC)c1ncco1
• InChI: 1S/3C4H9.C3H2NO.Sn/c3*1-3-4-2;1-2-5-3-4-1;/h3*1,3-4H2,2H3;1-2H;
• InChIKey: YOWGRWHKDCHINP-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

2-(Tri-n-butylstannyl)oxazole is a synthetic building block used in Stille coupling reaction.

Anwendung

2-(Tri-n-butylstannyl)oxazole can be used as a reactant to prepare:

• Heteroaromatic compounds via Stille-Migita cross-coupling reaction with (hetero)aryl halides using a palladium catalyst.
• Ethyl 2-[3-(1,3-oxazol-2-yl)-1H-indazol-1-yl]acetate by reacting with 3-iodoindazole in the presence of Pd(PPh₃)₄ as a catalyst.

Sicherheitshinweise

• Piktogramme: GHS06,GHS08,GHS09
• Signalwort: Danger
• H-Sätze: H301,H312,H315,H319,H360FD,H372,H410
• P-Sätze: P202 - P273 - P280 - P301 + P310 - P302 + P352 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 1
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter