420069

Chlorameisensäure-6-nitroveratrylester

97%, for peptide synthesis

• Synonym(e): 4,5-Dimethoxy-2-nitrobenzylchlorformiat, 6-Nitroveratryl-chlorformiat, 6-Nitroveratryloxycarbonyl-chlorid, NVOC-Cl, NVOC-chlorid
• Lineare Formel: ClCO₂CH₂C₆H₂(OCH₃)₂NO₂
• CAS-Nummer: 42855-00-5
• Molekulargewicht: 275.64
• Beilstein: 2389168
• MDL-Nummer: MFCD00143507
• UNSPSC-Code: 12352101
• PubChem Substanz-ID: 24866307
• NACRES: NA.22

Eigenschaften

• product name: Chlorameisensäure-6-nitroveratrylester, 97%
• Assay: 97%
• Form: powder
• mp (Schmelzpunkt): 125 °C (dec.) (lit.)
• Anwendung(en): peptide synthesis
• Lagertemp.: 2-8°C
• SMILES String: COc1cc(COC(Cl)=O)c(cc1OC)[N+]([O-])=O
• InChI: 1S/C10H10ClNO6/c1-16-8-3-6(5-18-10(11)13)7(12(14)15)4-9(8)17-2/h3-4H,5H2,1-2H3
• InChIKey: RWWPKIOWBQFXEE-UHFFFAOYSA-N

Beschreibung

Anwendung

4,5-Dimethoxy-2-nitrobenzyl chloroformate (NVOC-Cl) is a photolabile protecting reagent, commonly used in peptide or nucleotide synthesis to protect amines and hydroxyl groups. General applications are:

• Preparation of inactive, caged protein conjugates which can be activated by irradiating near-ultraviolet light.
• Solid-phase synthesis of base-sensitive S-acylthioethyl (SATE)-prooligonucleotides.
• Modification of surface properties by introducing photocleavable NVOC moiety into chitosan to control cell attachment.

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H314
• P-Sätze: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Gefahreneinstufungen: Skin Corr. 1B
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges