104256

Ethyl-p-toluolsulfonat

98%

• Synonym(e): Ethyl 4-methylbenzenesulfonate, Ethyl tosylate
• Lineare Formel: CH₃C₆H₄SO₃C₂H₅
• CAS-Nummer: 80-40-0
• Molekulargewicht: 200.25
• Beilstein: 611213
• EG-Nummer: 201-276-7
• MDL-Nummer: MFCD00009100
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24846433
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Assay: 98%
• Form: solid
• Brechungsindex: n20/D 1.511 (lit.)
• bp: 158-162 °C/10 mmHg (lit.)
• mp (Schmelzpunkt): 29-33 °C (lit.)
• Dichte: 1.174 g/mL at 25 °C (lit.)
• SMILES String: CCOS(=O)(=O)c1ccc(C)cc1
• InChI: 1S/C9H12O3S/c1-3-12-13(10,11)9-6-4-8(2)5-7-9/h4-7H,3H2,1-2H3
• InChIKey: VRZVPALEJCLXPR-UHFFFAOYSA-N

Beschreibung

Anwendung

Ethyl p-toluenesulfonate was used in a study to develop a fast and accurate method for determination of residues of some common alkylating agents employed in drug synthesis by in situ derivatization–headspace–gas chromatography–mass spectrometry. Ethyl p-toluenesulfonate was used to develop an extraction method for methyl and ethyl esters of various sulfonic acids in active pharmaceutical ingredients using solid-phase microextraction coupled to GC/MS in the selected ion monitoring mode.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): 316.4 °F - closed cup
• Flammpunkt (°C): 158 °C - closed cup
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves