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324558

Sigma-Aldrich

Ethylene glycol

anhydrous, 99.8%

Synonym(s):

1,2-Ethanediol

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About This Item

Linear Formula:
HOCH2CH2OH
CAS Number:
107-21-1
Molecular Weight:
62.07
Beilstein/REAXYS Number:
505945
EC Number:
203-473-3
MDL number:
MFCD00002885
UNSPSC Code:
12191502
eCl@ss:
39020501
PubChem Substance ID:
57648687
NACRES:
NA.21

grade

anhydrous

Quality Level

100

vapor density

2.1 (vs air)

vapor pressure

0.08 mmHg ( 20 °C)

assay

99.8%

form

liquid

autoignition temp.

752 °F

expl. lim.

15.3 %

impurities

<0.003% water
<0.005% water (100 mL pkg)

refractive index

n20/D 1.431 (lit.)

bp

195-198 °C

mp

−13 °C (lit.)

density

1.113 g/mL at 25 °C (lit.)

SMILES string

OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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General description

Ethylene glycol is the major component of antifreeze preparations.

Application

Ethylene glycol may be used in the preparation of spiroborate esters by reacting with chiral 1,2-aminoalcohols in the presence of triisopropyl borate. It may also be used as a solvent in the preparation of tris(2,2′-bipyrazyl)ruthenium(II) chloride by the reaction of 2,2′-bipyrazine with ruthenium(III) chloride.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

hcodes

H302,H373

Hazard Classifications

Acute Tox. 4 Oral - STOT RE 2 Oral

target_organs

Kidney

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

239.0 °F - open cup

flash_point_c

115 °C - open cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
SHBP0020
SHBN7674
SHBN5350
SHBN1629
SHBN0801

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Ethylene glycol United States Pharmacopeia (USP) Reference Standard

USP

1265515

Ethylene glycol

Adipoyl chloride 98%

Sigma-Aldrich

165212

Adipoyl chloride

The spectrum of ethylene glycol poisoning.
Moriarty RW & McDonald RH.
Clinical Toxicology, 7(6), 583-596 (1974)
Synthesis of spiroborate esters from 1,2-aminoalcohols, ethylene glycol and triisopropyl borate: preparation of (S)-1-(1,3,2-dioxaborolan-2-yloxy)-3-methyl-1,1-diphenylbutan-2-amine
Stepanenko V, et al.
Organic Syntheses, 87, 26-26 (2010)
Bis(tetrakis(3,5-bis(trifluoromethyl)phenyl)borate)
Lies SD, et al.
Organic Syntheses, 93, 178-178 (2016)
Teodora Miclăuş et al.
Nano letters, 14(4), 2086-2093 (2014-03-13)
Protein coronas around silver nanocubes were quantified in serum-containing media using localized surface plasmon resonances. Both soft and hard coronas showed exposure-time and concentration-dependent changes in protein surface density with time-dependent hardening. We observed spatially dependent kinetics of the corona-formation
Gregory Charles Nordmann et al.
Scientific reports, 10(1), 915-915 (2020-01-24)
The transcription factor ZENK is an immediate early gene that has been employed as a surrogate marker to map neuronal activity in the brain. It has been used in a wide variety of species, however, commercially available antibodies have limited
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