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CCL2

chemokine (C-C motif) ligand 2

Synonyms:
GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF
Species:
UniProtKB ID:
Gene ID:
  • Human(6347) Summary: This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2008]
  • Mouse(20296) chemokine (C-C motif) ligand 2
  • Rat(24770) chemokine (C-C motif) ligand 2
  • naked mole-rat(101697988) chemokine (C-C motif) ligand 2
  • domestic guinea pig(100135494) chemokine (C-C motif) ligand 2
  • sheep(101120093) chemokine (C-C motif) ligand 2
  • Domestic Rabbit(100009130) chemokine (C-C motif) ligand 2
  • sheep(100294591) chemokine (C-C motif) ligand 2
  • dog(403981) chemokine (C-C motif) ligand 2
  • cow(281043) chemokine (C-C motif) ligand 2
  • Horse(100034136) chemokine (C-C motif) ligand 2

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ELISA

Product Number
Description
Species
Mouse MCP-1 / CCL2 ELISA Kit, for cell and tissue lysates,
Species
mouse
Mouse MCP-1 / CCL2 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse
Rat MCP-1 / CCL2 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
rat
Rat MCP-1 / CCL2 ELISA Kit, for cell and tissue lysates,
Species
rat
Equine MCP-1 ELISA, for serum, plasma and cell culture supernatants,
Species
horse

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-Monocyte Chemotactic Protein-1 antibody produced in mouse, clone 24822, purified immunoglobulin, lyophilized powder,
Species Reactivity
human
Application
neutralization
western blot
Anti-MCP-1 Antibody, clone 2G17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunofluorescence

immunohistochemistry

western blot
Anti-Monocyte Chemotactic Protein-1 Antibody, Chemicon®, from rabbit,
Species Reactivity
rat
Application
ELISA
neutralization

western blot
Anti-CCL2 Antibody, clone 2D8, clone 2D8, from mouse,
Species Reactivity
human, monkey, mouse, rat
Application
flow cytometry
immunofluorescence

immunohistochemistry

western blot
Human MCP-1 Conferma® ELISA, quantification of human MCP-1 in serum, plasma, or culture media samples.,
Species Reactivity
human
Application
ELISA

Proteins

Product Number
Description
Species
JE/MCP-1 (CCL2) from mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
mouse
MCP-1/MCAF human, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human
SILuProt CCL2 C-C motif chemokine 2 human, SIL MS Protein Standard, 13C and 15N-labeled,
Species
human
SILuLite CCL2 C-C motif chemokine 2 human, recombinant, expressed in HEK 293 cells, MS Protein Standard,
Species
human
Monocyte Chemotactic Protein-1, Recombinant rat, The Macrophage/monocyte chemoattractant protein-1 (or MCP-1 protein) plays an important role in the inflammatory response of blood monocytes & tissue macrophages.,
Species
rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CCL2,
Species
human
MISSION® esiRNA, targeting mouse Ccl2,
Species
mouse