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Key Documents

SRP0332

Sigma-Aldrich

FYN A active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥60% (SDS-PAGE)

Synonym(s):

FYN oncogene related to SRC, FGR, YES, p59-FYN

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in baculovirus infected Sf9 cells

assay

≥60% (SDS-PAGE)

form

aqueous solution

mol wt

61 kDa

packaging

pkg of 10 μg

technique(s)

activity assay: suitable
inhibition assay: suitable

NCBI accession no.

NM_002037

UniProt accession no.

P06241

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... FYN(2534)

General description

Human FYN A (GenBank Accession No. NM_002037), full length, amino acids 2-537 (end) with N-terminal Flag-tag, MW= 61 kDa, expressed in Sf9 insect cells.

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Physical form

Fomulated in 45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 18 mM glutathione, and 10% glycerol.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Kathleen E McGrath et al.
Blood, 111(4), 2409-2417 (2007-11-23)
Enucleation is the hallmark of erythropoiesis in mammals. Previously, we determined that yolk sac-derived primitive erythroblasts mature in the bloodstream and enucleate between embryonic day (E)14.5 and E16.5 of mouse gestation. While definitive erythroblasts enucleate by nuclear extrusion, generating reticulocytes
Hyang-Sook Hoe et al.
The Journal of biological chemistry, 283(10), 6288-6299 (2007-12-20)
Dab1 is an intracellular adaptor protein that interacts with amyloid precursor protein (APP) and apoE receptor 2 (apoEr2), increases their levels on the cell surface, and increases their cleavage by alpha-secretases. To investigate the mechanism underlying these alterations in processing

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