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SML3426

Sigma-Aldrich

Glycerol phenylbutyrate

≥95% (HPLC)

Synonym(s):

1,2,3-Propanetriyl tris(4-phenylbutanoate), GPB, Glyceryl tri-[4-phenylbutyrate, HPN 100, Tri(4-phenylbutyryl)glycerol

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About This Item

Empirical Formula (Hill Notation):
C33H38O6
CAS Number:
611168-24-2
Molecular Weight:
530.65
MDL number:
MFCD28016960
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

assay

≥95% (HPLC)

form

oil

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

O=C(OCC(OC(CCCC1=CC=CC=C1)=O)COC(CCCC2=CC=CC=C2)=O)CCCC3=CC=CC=C3

Biochem/physiol Actions

Glycerol phenylbutyrate, a triacylglycerol, is a prodrug of ER stress inhibitor 4-phenylbutyric acid (PBA). Glycerol phenylbutyrate is a nitrogen-binding agent approved for the chronic management of adult and pediatric patients (≥2 years of age) with urea cycle disorders (UCDs) who cannot be managed by dietary protein restriction and/or amino acid supplementation alone.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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