SAB5700469

Anti-Phospho-MYH9-S1943 antibody produced in rabbit

• Synonym(s): BDPLT6, DFNA17, EPSTS, FTNS, MHA, MYH9, NMHC-II-A, NMMHC-IIA, NMMHCA, myosin-9
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 159; 226
• species reactivity: rat, mouse, human
• concentration: 1.8 mg/ml
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: P35579
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer1943)
• Gene Information: human ... MYH9(4627)

Description

General description

This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.

Immunogen

A synthetic phosphorylated peptide around S1943 of human MYH9 (NP_002464.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable