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Key Documents

SAB4700770

Sigma-Aldrich

Monoclonal Anti-EBV antigen EBNA-1 antibody produced in mouse

clone E1-2.5, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Ebna1 Antibody, Ebna1 Antibody - Monoclonal Anti-EBV antigen EBNA-1 antibody produced in mouse

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

E1-2.5, monoclonal

form

buffered aqueous solution

species reactivity

Epstein-Barr virus

concentration

1 mg/mL

technique(s)

immunocytochemistry: suitable
indirect ELISA: suitable

isotype

IgG2b

NCBI accession no.

YP_401677.1

shipped in

wet ice

storage temp.

2-8°C

Gene Information

Epstein-Barr virus ... EBNA-1(3783709)

General description

The antibody E1-2.5 recognizes repetitive Gly-Ala region of the Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA-1). EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.

Immunogen

EBNA-1

Biochem/physiol Actions

Epstein–Barr nuclear antigen 1 (EBNA-1) plays an essential role in the replication of the Epstein-Barr virus (EBV) genome as an extrachromosomal element. In addition, it also regulates transcription of a EBV latent gene expression. EBNA-1 is essential for maintenance of EBV in episomal form.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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EBNA?1: a protein pivotal to latent infection by Epstein?Barr virus
Leight ER, et al.
Reviews in Medical Virology, 10(2), 83-100 (2000)
Antibody responses to Epstein-Barr virus-determined nuclear antigen (EBNA)-1 and EBNA-2 in acute and chronic Epstein-Barr virus infection
Henle W, et al.
Proceedings of the National Academy of Sciences of the USA, 84(2), 570-574 (1987)

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