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Key Documents

SAB3500882

Sigma-Aldrich

Monoclonal Anti-HIV-1 P24 antibody produced in mouse

clone 7F4, affinity isolated antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

7F4, monoclonal

form

buffered aqueous solution

species reactivity

virus

concentration

1 mg/mL

technique(s)

ELISA: suitable
immunoblotting: suitable

NCBI accession no.

AAB50258

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

P24 is a free human immunodeficiency virus (HIV) capsid antigen. This antigen forms a part of inner shell of the virus. P24 antigen test is usually done to estimate new drugs. This test also helps in diagnosis of pediatric HIV infection.

Immunogen

Antibody was raised against a recombinant full-length HIV-1 p24 protein.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 1 mg/mL in PBS with 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The Essential HIV Treatment Fact Book (1992)
Sexually Transmitted Infections (2014)
Measurement of HIV-1 p24 antigen by signal-amplification-boosted ELISA of heat-denatured plasma is a simple and inexpensive alternative to tests for viral RNA.
Schupbach J
AIDS Reviews, 4(2), 83-92 (2002)
Barbara J Flynn et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(17), 7131-7136 (2011-04-07)
Protein vaccines, if rendered immunogenic, would facilitate vaccine development against HIV and other pathogens. We compared in nonhuman primates (NHPs) immune responses to HIV Gag p24 within 3G9 antibody to DEC205 ("DEC-HIV Gag p24"), an uptake receptor on dendritic cells
T Goto et al.
Micron (Oxford, England : 1993), 29(2-3), 123-138 (1998-07-31)
The life-cycle of human immunodeficiency virus type 1 (HIV-1) has been studied using several techniques including immunoelectron microscopy and cryomicroscopy. The HIV-1 particle consists of an envelope, a core and the region between the core and the envelope (matrix). Virus
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