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Key Documents

SAB2702270

Sigma-Aldrich

Monoclonal Anti-ARHGEF18 antibody produced in mouse

clone GT1972, affinity isolated antibody

Synonym(s):

P114-RhoGEF

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
conjugate:
unconjugated
application:
IHC (p)
WB
clone:
GT1972, monoclonal
species reactivity:
rat, human, mouse
citations:
technique(s):
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:1,000
western blot: 1:500-1:3000

biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

GT1972, monoclonal

form

buffered aqueous solution

species reactivity

rat, human, mouse

concentration

1mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:1,000
western blot: 1:500-1:3000

isotype

IgG2a

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

Immunogen

Recombinant protein encompassing a sequence within the center region of human ARHGEF18.

Application

Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Biochem/physiol Actions

Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Other Notes

Purification: Affinity purified by Protein G

Physical form

Phosphate-buffered saline, no preservative added.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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