ARHGEF18
Rho/Rac guanine nucleotide exchange factor (GEF) 18
Synonyms:
P114-RhoGEF
Species:
Human ARHGEF18 (23370), Mouse Arhgef18 (102098), Rat Arhgef18 (304193), chicken ARHGEF18 (420132), domestic cat ARHGEF18 (101081026), dog ARHGEF18 (484991), cow ARHGEF18 (522521), domestic guinea pig Arhgef18 (100736199), naked mole-rat Arhgef18 (101722983), sheep ARHGEF18 (101122356)
UniProtKB ID:
Gene ID:
- Human(23370) Summary: Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
- Mouse(102098) rho/rac guanine nucleotide exchange factor (GEF) 18
- Rat(304193) rho/rac guanine nucleotide exchange factor (GEF) 18
- chicken(420132) rho/rac guanine nucleotide exchange factor (GEF) 18
- domestic cat(101081026) Rho/Rac guanine nucleotide exchange factor (GEF) 18
- dog(484991) Rho/Rac guanine nucleotide exchange factor (GEF) 18
- cow(522521) Rho/Rac guanine nucleotide exchange factor (GEF) 18
- domestic guinea pig(100736199) Rho/Rac guanine nucleotide exchange factor (GEF) 18
- naked mole-rat(101722983) Rho/Rac guanine nucleotide exchange factor (GEF) 18
- sheep(101122356) Rho/Rac guanine nucleotide exchange factor (GEF) 18
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ARHGEF18 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
Monoclonal Anti-ARHGEF18 antibody produced in mouse, clone GT1972, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-ARHGEF18 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-ARHGEF18 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry