S1450

Anti-Superoxide Dismutase (MnSOD) (DD-17)−Cy3 antibody produced in rabbit

1-2 mg/mL, affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-IPO-B, Anti-Indophenoloxidase B, Anti-MNSOD, Anti-Manganese Superoxide Dismutase 2, Anti-Manganese dependent SOD, Anti-Mitochondrial SOD, Anti-SOD2, Anti-Superoxide dismutase 2
• UNSPSC Code: 12352203
• NACRES: NA.43

Properties

• biological source: rabbit
• Quality Level: 200
• conjugate: CY3 conjugate
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human, rat, mouse
• packaging: antibody small pack of 25 μL
• concentration: 1-2 mg/mL
• technique(s): direct immunofluorescence: 2-5 μg/mL using human HeLa, rat NRK and mouse 3T3 cells.
• UniProt accession no.: P04179
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... SOD2(6648)

Description

General description

The SOD2 (superoxide dismutase 2) gene is mapped to human chromosome 6q25.3. The encoded protein functions as a tetramer and is localized to mitochondria.

Immunogen

synthetic peptide corresponding to amino acid residues 183-199 of human superoxide dismutase (MnSOD), conjugated to KLH. The corresponding sequence is conserved in many eukaryotes.

Application

Anti-Superoxide Dismutase (MnSOD) (DD-17)-Cy3 antibody produced in rabbit has been used in immunohistochemistry.

Biochem/physiol Actions

Superoxide dismutase 2 (SOD2) is an antioxidant enzyme and catalyzes the conversion of superoxide to hydrogen peroxide and molecular oxygen. The enzyme offers protection against oxidative damage induced by reactive oxygen species and is also radioprotective. The gene is associated with the metastasis and invasion process of salivary adenoid cystic carcinoma. Manganese SOD is involved in detoxification.

Physical form

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable