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Key Documents

RAB1177

Sigma-Aldrich

Mouse TSP-2 ELISA Kit

for cell culture supernatants, plasma, and serum samples

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

mouse

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type serum sample(s)
sample type plasma
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.16 ng/ml

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Thbs2(21826)

General description

This ELISA antibody pair detects Mouse Thrombospondin 2 (THBS2)

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Biochem/physiol Actions

Thrombospondin-2 (TSP2) is an extracellular matrix (ECM) protein involved in regulating fracture healing. In addition, it also regulates cell-matrix interactions. TSP2 plays a vital role in assembly of collagen fibrils in the skin. It is involved in tissue repair and foreign body responses. The matricellular protein TSP2 endogenously controls angiogenesis and inflammation in rheumatoid arthritis patients. It also acts as an endogenous inhibitor of tumor growth.

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

pictograms

Corrosion
GHS05

signalword

Warning

hcodes

H290

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Thrombospondin-2: a potent endogenous inhibitor of tumor growth and angiogenesis.
Streit M, et al.
Proceedings of the National Academy of Sciences of the USA, 96(26), 14888-14893 (1999)
Thrombospondin?2 influences the proportion of cartilage and bone during fracture healing.
Taylor D K, et al.
Journal of Bone and Mineral Research, 24(6), 1043-1054 (2009)
The functions of thrombospondin-1 and-2.
Lawler J
Current Opinion in Cell Biology, 12(5), 634-640 (2000)
Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in rheumatoid arthritis.
Park Y W, et al.
The American Journal of Pathology, 165(6), 2087-2098 (2004)

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