I3766
Isoliquiritigenin
powder
Synonym(s):
(E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one, 4,2′,4′-Trihydroxychalcone
About This Item
Recommended Products
form
powder
Quality Level
color
yellow to orange
solubility
H2O: <0.1 mg/mL
methanol: 10 mg/mL
DMSO: 20 mg/mL
storage temp.
2-8°C
SMILES string
Oc1ccc(cc1)\C=C\C(=O)c2ccc(O)cc2O
InChI
1S/C15H12O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9,16-17,19H/b8-3+
InChI key
DXDRHHKMWQZJHT-FPYGCLRLSA-N
Gene Information
rat ... Alox5(25290)
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General description
Application
- as a bone morphogenetic protein (BMP) agonist in zebrafish embryos
- as a guanylyl cyclase activator in zebrafish embryos
- to test its antitumor and antiviral effects against Epstein-Barr virus-associated gastric carcinoma
Biochem/physiol Actions
Features and Benefits
Caution
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Certificates of Analysis (COA)
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Cyclic nucleotides, including cyclic AMP (cAMP), cyclic GMP (cGMP) and cyclic ADP-ribose, have been extensively studied as second messengers of intracellular events initiated by activation of GPCRs. cAMP modifies cell function in all eukaryotic cells, principally through the activation of cAMP-dependent protein kinase (PKA), but also through cAMP-gated ion channels and guanine nucleotide exchange factors directly activated by cAMP.
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