SML2132

Brazilin

• Synonym(s): Brasilin, (+)-Brazilin, (6aS,11bR)-7,11b-Dihydro-benz[b]indeno[1,2-d]pyran-3,6a,9,10(6H)-tetrol, 7, 11b-dihydrobenz[b]indeno[1,2-d]pyran-3,6a,9,10 (6H)-tetrol, NSC 56652, 6,6a,7,11b-Tetrahydro-3,6a,9,10-tetrahydroxyindeno[2,1-c]chromene, Natural Red 24
• Empirical Formula (Hill Notation): C₁₆H₁₄O₅
• CAS Number: 474-07-7
• Molecular Weight: 286.28
• Colour Index Number: 75280
• EC Number: 207-477-6
• MDL number: MFCD00210817
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• optical activity: [α]/D 108.0 to 133.0°, c = 0.5 in methanol
• color: white to very dark brown
• solubility: DMSO: 2 mg/mL
• storage temp.: 2-8°C
• SMILES string: O1C[C@]2([C@@H](c4c1cc(cc4)O)c3c(cc(c(c3)O)O)C2)O
• InChI: 1S/C16H14O5/c17-9-1-2-10-14(4-9)21-7-16(20)6-8-3-12(18)13(19)5-11(8)15(10)16/h1-5,15,17-20H,6-7H2/t15-,16+/m0/s1
• InChI key: UWHUTZOCTZJUKC-JKSUJKDBSA-N

Description

Biochem/physiol Actions

Brazilin is a natural isoflavonoid red pigment with many biologic activities including neuroprotective, anti-inflammatory, antibacterial, antiproliferative, and antioxidant properties. Some of its activity is thought to be due to its regulation of the transcription factor NF-ΚB.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable