H6269

Hexadecyltrimethylammonium bromide

for molecular biology, ≥99%

• Synonym(s): CTAB, Cetrimonium bromide, Cetyltrimethylammonium bromide, Palmityltrimethylammonium bromide
• Linear Formula: CH₃(CH₂)₁₅N(Br)(CH₃)₃
• CAS Number: 57-09-0
• Molecular Weight: 364.45
• Beilstein: 3598189
• EC Number: 200-311-3
• MDL number: MFCD00011772
• PubChem Substance ID: 24895734
• NACRES: NA.31

Properties

• grade: for molecular biology
• Quality Level: 200
• description: cationic
• Assay: ≥99%
• form: powder or crystals
• mol wt: micellar avg mol wt 62,000
• aggregation number: 170
• pH: 5.0-7 (25 °C, 36.4 g/L)
• CMC: 0.92; 1 mM (20-25°C)
• mp: 248-251 °C (lit.)
• solubility: H₂O: 1/10 g/mL
• HLB: 10
• suitability: suitable for DNA precipitation
• foreign activity: DNAse, none detected; Endonuclease, none detected; Exonuclease, none detected; NICKase, none detected; RNAse, none detected
• SMILES string: [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C
• InChI: 1S/C19H42N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(2,3)4;/h5-19H2,1-4H3;1H/q+1;/p-1
• InChI key: LZZYPRNAOMGNLH-UHFFFAOYSA-M

Description

Application

Hexadecyltrimethylammonium bromide has been used:

• as a component of DNA extraction buffer and RNA extraction buffer
• as a constituent of dye dissolution buffer
• as a surfactant in gold nanorod preparation.

Biochem/physiol Actions

Hexadecyltrimethylammonium bromide also called cetyltrimethylammonium bromide (CTAB), is a cationic surfactant. CTAB method is an efficient, cost and time effective method of DNA extraction. CTAB is used as a shaping material and reducing agent for nanoparticle generation.

Safety Information

• Pictograms: GHS05,GHS07,GHS08,GHS09
• Signal Word: Danger
• Hazard Statements: H302 - H315 - H318 - H335 - H373 - H410
• Precautionary Statements: P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT RE 2 Oral - STOT SE 3
• Target Organs: Gastrointestinal tract, Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): 471.2 °F - closed cup
• Flash Point(C): 244 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves