H5916

Human Growth Hormone human

HGH, recombinant, expressed in HEK 293 cells, HumanKine^®, suitable for cell culture

• Synonym(s): Anti-PECAM-1
• NACRES: NA.77

Properties

• Quality Level: 100
• biological source: human
• recombinant: expressed in HEK 293 cells
• assay: ≥95% (SDS-PAGE)
• form: lyophilized powder
• potency: ≤0.5 ng/mL EC₅₀
• mol wt: monomer 22 kDa (non-glycosylated)
• packaging: pkg of 10 μg
• storage condition: avoid repeated freeze/thaw cycles
• technique(s): cell culture | mammalian: suitable
• impurities: ≤1 EU/mg
• storage temp.: −20°C

Description

Packaging

10 μg in poly bottle

Biochem/physiol Actions

HGH is a member of the somatotropin/prolactin family of hormones. HGH is produced from the pituitary gland and is required for normal human growth and development. HGH modifies a variety of physiological functions by stimulating the expression of insulin-like growth factor I, and increases calcium retention and bone mineralization. HGH increases muscle mass, promotes lipolysis, and reduces liver uptake of glucose.

Physical form

Lyophilized from a 0.2 μm filtered solution of 1x PBS.

Preparation Note

HumanKine, Human Growth Hormone (HGH) is expressed as a non-glycosylated monomer in human HEK 293 cells and has an apparent molecular mass of 22 kDa.

Analysis Note

The activity was determined by the dose-dependent stimulation of the proliferation of rat lymphoma line Nb2-11 cells (prolactin indicator cell line).

Legal Information

HumanKine is a registered trademark of Proteintech Group, Inc.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable