D5670

Sodium deoxycholate monohydrate

BioXtra, ≥99.0% (titration)

• Synonym(s): 3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt
• Empirical Formula (Hill Notation): C₂₄H₃₉NaO₄ · H₂O
• CAS Number: 145224-92-6
• Molecular Weight: 432.57
• Beilstein/REAXYS Number: 3643164
• EC Number: 206-132-7
• MDL number: MFCD00150750
• UNSPSC Code: 12161900
• PubChem Substance ID: 24893956
• NACRES: NA.25

Properties

• description: anionic
• product line: BioXtra
• assay: ≥99.0% (titration)
• form: powder
• optical activity: [α]20/D +44±2° in H₂O(lit.)
• mol wt: 432.57 g/mol
• technique(s): electrophoresis: suitable; immunoprecipitation (IP): suitable
• impurities: Insoluble matter, passes filter test; ≤0.5% Cholic acid
• pH: 7.5-9.5 (20 °C, 0.1 M in H₂O)
• solubility: H₂O: 0.1 M, clear, colorless
• anion traces: sulfate (SO₄^2-): ≤0.02%
• cation traces: Al: ≤0.002%; Ba: ≤0.0005%; Bi: ≤0.0005%; Ca: ≤0.05%; Cd: ≤0.0005%; Co: ≤0.0005%; Cr: ≤0.0005%; Cu: ≤0.0005%; Fe: ≤0.001%; K: ≤0.010%; Li: ≤0.0005%; Mg: ≤0.002%; Mn: ≤0.0005%; Mo: ≤0.0005%; Ni: ≤0.0005%; Pb: ≤0.0005%; Sr: ≤0.002%; Zn: ≤0.0005%
• absorption: ≤0.08 at 280 in H₂O at 0.1 M; ≤0.10 at 260 in H₂O at 0.1 M
• SMILES string: O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3CCC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C
• InChI: 1S/C24H40O4.Na.H2O/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);;1H2/q;+1;/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;;/m1../s1
• InChI key: NDVHNZISGVSFMP-WTCAICSISA-M

Description

General description

Sodium deoxycholate (SDC) monohydrate is a bile acid salt.

Application

Sodium deoxycholate monohydrate has been used in a study to assess a method for the immobilization of lipoxygenase in an alginate-silicate gel matrix. It has also been used in a study to investigate the in vitro dissolution of gall stones.

Powerful solubilization agent; used in the solubilization of estrogen synthetase from human placental microsomes.

Biochem/physiol Actions

Bile Salt

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves