All Photos(5)

D4641

Sigma-Aldrich

n-Dodecyl β-D-maltoside

≥98% (GC)

Synonym(s):
DDM, Lauryl-β-D-maltoside
Empirical Formula (Hill Notation):
C24H46O11
CAS Number:
Molecular Weight:
510.62
Beilstein:
55318
MDL number:
eCl@ss:
32190102
PubChem Substance ID:
NACRES:
NA.25

Quality Level

description

non-ionic

assay

≥98% (GC)

mol wt

micellar avg mol wt 50,000

aggregation number

98

technique(s)

protein quantification: suitable

CMC

0.15 mM (20-25°C)

mp

224-226 °C (lit.)

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O

InChI

1S/C24H46O11/c1-2-3-4-5-6-7-8-9-10-11-12-32-23-21(31)19(29)22(16(14-26)34-23)35-24-20(30)18(28)17(27)15(13-25)33-24/h15-31H,2-14H2,1H3/t15-,16-,17-,18+,19-,20-,21-,22-,23-,24-/m1/s1

InChI key

NLEBIOOXCVAHBD-QKMCSOCLSA-N

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General description

n-Dodecyl β-D-maltoside is a surfactant.

Application

Non-ionic detergent for the stabilization and activation of enzymes and for membrane research.
n-Dodecyl β-D-maltoside has been used in a study to assess the mapping of unfolding states of integral helical membrane proteins by GPS-NMR and scattering techniques.

Packaging

500 mg in poly bottle
1, 5, 25 g in poly bottle

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Certificate of Origin

Kenneth P Watkins et al.
The Plant journal : for cell and molecular biology, 102(2), 369-382 (2019-12-04)
Synthesis of the D1 reaction center protein of Photosystem II is dynamically regulated in response to environmental and developmental cues. In chloroplasts, much of this regulation occurs at the post-transcriptional level, but the proteins responsible are largely unknown. To discover
Ka Young Chung et al.
The Journal of biological chemistry, 287(43), 36305-36311 (2012-08-16)
The G protein-coupled β(2)-adrenoreceptor (β(2)AR) signals through the heterotrimeric G proteins G(s) and G(i) and β-arrestin. As such, the energy landscape of β(2)AR-excited state conformers is expected to be complex. Upon tagging Cys-265 of β(2)AR with a trifluoromethyl probe, (19)F
Electrochemistry, AFM, and PM-IRRA spectroscopy of immobilized hydrogenase: role of a hydrophobic helix in enzyme orientation for efficient H2 oxidation.
Alexandre Ciaccafava et al.
Angewandte Chemie (International ed. in English), 51(4), 953-956 (2011-12-17)
Signe Beck Petersen et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 47(4), 701-712 (2012-09-07)
Alkylmaltosides are a class of non-ionic surfactant currently in clinical trials to improve nasal permeation of peptide drugs, however few studies have detailed their potential effects on intestinal permeation enhancement. Tetradecyl maltoside (TDM, C(14)), was examined in Caco-2 monolayers and
Ryutaro Tokutsu et al.
The Journal of biological chemistry, 287(37), 31574-31581 (2012-07-18)
Photosystem II (PSII) is a multiprotein complex that splits water and initiates electron transfer in photosynthesis. The central part of PSII, the PSII core, is surrounded by light-harvesting complex II proteins (LHCIIs). In higher plants, two or three LHCII trimers

Protocols

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