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A1345

Sigma-Aldrich

Antioxidant Supplement (1000×)

liquid, sterile-filtered, suitable for cell culture

Synonym(s):

Antioxidant Solution

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About This Item

UNSPSC Code:
12352205
NACRES:
NA.75

sterility

sterile-filtered

form

liquid

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

shipped in

ambient

storage temp.

2-8°C

General description

Antioxidant Supplement (1000×) is a proprietary medium supplement specially formulated to boost cell growth for enhanced viral and protein expression. It may be used in combination with Polyamine Supplement (P 8483).
One mL supplements 1 liter of medium.

Application

Antioxidant Supplement (1000×) has been used:

  • as a component of the extender media for dilution of sperm samples during cryopreservation
  • for long term culture of human-induced pluripotent stem (iPS) cells
  • as a component of the immortalization media used for culturing, cloning and expansion of clones for making immortalized cell lines from embryonic mouse kidney

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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E Cabrita et al.
Animal reproduction science, 125(1-4), 189-195 (2011-04-13)
During cryopreservation, dilution in the extender media reduces the seminal plasma constituents being cells more vulnerable to oxidative stress. Vitamins (C and E) and the amino acids taurine and hypotaurine are powerful antioxidants naturally present in seminal plasma. Whether their
Kendall Mitchell et al.
BMC neuroscience, 17(1), 80-80 (2016-12-03)
Bone morphogenetic protein-2 (BMP-2) is a pleiotropic, secreted molecule with diverse effects. The potent ability of BMP-2 to stimulate bone growth prompted its widespread clinical use for arthrodesis (spine fusion). However, elevated post-operative pain in patients treated with BMP-2 has
Lan Luo et al.
Scientific reports, 4, 3779-3779 (2014-01-22)
Effects of antioxidants on the quality and genomic stability of induced pluripotent stem (iPS) cells were investigated with two human iPS cell lines (201B7 and 253G1). Cells used in this study were expanded from a single colony of each cell
Michael R Duggan et al.
Cell death discovery, 7(1), 60-60 (2021-03-28)
Despite increasing numbers of aged individuals living with HIV, the mechanisms underlying HIV-associated neurological disorders (HANDs) remain elusive. As HIV-1 pathogenesis and aging are characterized by oxidative stress as well as altered protein quality control (PQC), reactive oxygen species (ROS)
Amanda McQuade et al.
Nature communications, 11(1), 5370-5370 (2020-10-25)
The discovery of TREM2 as a myeloid-specific Alzheimer's disease (AD) risk gene has accelerated research into the role of microglia in AD. While TREM2 mouse models have provided critical insight, the normal and disease-associated functions of TREM2 in human microglia

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