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71859

Sigma-Aldrich

Sodium (meta)periodate

BioUltra, ≥99.5% (RT)

Synonym(s):
Sodium periodate
Linear Formula:
NaIO4
CAS Number:
Molecular Weight:
213.89
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

product line

BioUltra

Quality Level

assay

≥99.5% (RT)

form

crystals

impurities

insoluble matter, passes filter test

loss

≤0.1% loss on drying, 20 °C (HV)

pH

3.5-5.5 (25 °C, 0.5 M in H2O)

solubility

H2O: 0.5 M at 20 °C, clear, colorless

anion traces

bromide, bromate, chloride, chlorate (as Cl-): ≤100 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

absorption

cut-off at 350 nm in H2O at 0.05 M

SMILES string

[Na+].[O-]I(=O)(=O)=O

InChI

1S/HIO4.Na/c2-1(3,4)5;/h(H,2,3,4,5);/q;+1/p-1

InChI key

JQWHASGSAFIOCM-UHFFFAOYSA-M

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Application

Sodium periodate is use in molecular biology and carbohydrate research to cleave carbon-carbon bonds of carbohydrates alginates, chitosans, hyaluronan, scleroglucan/schizophyllan, cellulose nucleic acids other molecules rich in hydroxyls and ketones to prepare them for chemical and physical modifications.
Useful reagent for the oxidation of carbohydrates prior to labeling with biotin hydrazide

Other Notes

Periodate oxidation of agarose gels in enzyme immobilization; Preparation of oligonucleotide 3′-dialcohols in ribonucleoside labeling; Cleavage of cross-linked proteins.

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Ox. Sol. 1 - Skin Corr. 1C - STOT RE 1

Target Organs

thymus gland

Storage Class Code

5.1A - Strongly oxidizing hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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