302031

Sigma-Aldrich

Trifluoroacetic acid

suitable for HPLC, ≥99.0%

Synonym(s):
TFA
Linear Formula:
CF3COOH
CAS Number:
Molecular Weight:
114.02
Beilstein/REAXYS Number:
742035
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

vapor density

3.9 (vs air)

vapor pressure

97.5 mmHg ( 20 °C)

assay

≥99.0%

form

liquid

application(s)

HPLC: suitable
UV/Vis spectroscopy: suitable

impurities

<0.050% water

evapn. residue

<0.005%

refractive index

n20/D 1.3 (lit.)

pH

1 (20 °C, 10  g/L)

bp

72.4 °C (lit.)

mp

−15.4 °C (lit.)

solubility

water: soluble

density

1.489 g/mL at 20 °C (lit.)

λ

H2O reference

UV absorption

λ: 260 nm Amax: 0.9
λ: 270 nm Amax: 0.10
λ: 280 nm Amax: 0.05
λ: 290 nm Amax: 0.04
λ: 300 nm Amax: 0.03
λ: 320 nm Amax: 0.025

Featured Industry

Food and Beverages

SMILES string

OC(C(F)(F)F)=O

InChI

1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI key

DTQVDTLACAAQTR-UHFFFAOYSA-N

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Related Categories

Packaging

1 L in glass bottle
10×1 mL in ampule
100, 4×100 mL in glass bottle

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Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

hazcat

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A

storage_class_code

8A - Combustible, corrosive hazardous materials

WGK Germany

WGK 2

Flash Point(F)

212.0 °F - Pensky-Martens closed cup

Flash Point(C)

> 100 °C - Pensky-Martens closed cup

Certificate of Analysis

Certificate of Origin

Kwang Su Kim et al.
ACS applied materials & interfaces, 5(9), 3591-3598 (2013-04-05)
Graphene-based electrochemical impedance sensors have recently received much attention due to their outstanding sensing capability and economic viability. In this study, we present a novel means of constructing an impedance sensing platform via harnessing intrinsic π-stacking interactions between probe protein...
Guangfa Shi et al.
Organic letters, 17(1), 38-41 (2014-12-18)
Direct trifluoromethylation of arenes using TFA as the trifluoromethylating reagent was achieved with Ag as the catalyst. This reaction not only provides a new protocol for aryl C-H trifluoromethylation, but the generation of CF3· from TFA may prove useful in...
Risto Kostiainen et al.
Journal of chromatography. A, 1216(4), 685-699 (2008-09-19)
The most widely used ionization techniques in liquid chromatography-mass spectrometry (LC-MS) are electrospray ionization (ESI), atmospheric pressure chemical ionization (APCI) and atmospheric pressure photoionization (APPI). All three provide user friendly coupling of LC to MS. Achieving optimal LC-MS conditions is...
W C Mahoney et al.
The Journal of biological chemistry, 255(23), 11199-11203 (1980-12-10)
A method employing reverse phase high performance liquid chromatography has been developed for the purification of large denatured peptides. The cyanogen bromide fragments of hemoglobin alpha, beta, and gamma chains (13 to 91 residues in length) could be separated and...
Macro- and micromethods for the determination of serum vitamin A using trifluoroacetic acid.
J B NEELD et al.
The Journal of nutrition, 79, 454-462 (1963-04-01)
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