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Sodium fluoride

ACS reagent, ≥99%

Linear Formula:
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level


ACS reagent

vapor pressure

1.4 mmHg ( 0 °C)






≤0.01 meq/g Titr. base
≤0.02% insolubles
≤0.03 meq/g Titr. acid
≤0.1% sodium fluorosilicate


≤0.3% loss on drying


993 °C (lit.)

anion traces

chloride (Cl-): ≤0.005%
sulfate (SO42-): ≤0.03%
sulfite (SO32-): ≤0.005%

cation traces

Fe: ≤0.003%
K: ≤0.02%
heavy metals (as Pb): ≤0.003%

SMILES string




InChI key


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General description

Sodium fluoride (NaF) is a metallic halide. It has been reported as dental caries preventive agent. It is the most widely employed chemical preservative for the preservation of glucose in blood. It has been reported to stabilize the hepatic microsomal glucose-6-P phosphohydrolase enzyme.


Sodium fluoride may be used as a fluorinating agent for chlorine-containing compounds via halogen-exchange reaction.
Starting material for solid state preparation of Na3MnF6 for further high pressure structural determination studies.
Sodium fluoride may be employed as a fluorination agent in the synthesis of aromatic and aliphatic fluorides. It may be used to prepare the lysis buffer.


5, 100, 500 g in poly bottle


Skull and crossbones

Signal Word


Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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More Documents

Quotes and Ordering

The effect on human dental caries of weekly oral rinsing with a sodium fluoride mouthwash: a final report.
Horowitz HS, et al.
Archives of Oral Biology, 16(6), 609-616 (1971)
A prospective, randomized clinical study on the effects of an amine fluoride/stannous fluoride toothpaste/mouthrinse on plaque, gingivitis and initial caries lesion development in orthodontic patients.
?gaard B, et al.
European Journal of Orthodontics, 28(1), 8-12 (2006)
A J Lange et al.
The Journal of biological chemistry, 261(1), 101-107 (1986-01-05)
Stabilization and inhibition of hepatic microsomal glucose-6-P phosphohydrolase (EC by F- requires the presence of Al3+ ions. At millimolar concentrations, reagent grade NaF inhibited glucose-6-P hydrolysis and protected the enzyme against inactivation induced by heat in the presence of
Effectiveness of sodium fluoride as a preservative of glucose in blood.
Chan AY, et al.
Clinical Chemistry, 35(2), 315-317 (1989)
Synthesis of fluorides by metathesis with sodium fluoride.
Tullock CW and Coffman DD.
The Journal of Organic Chemistry, 25(11), 2016-2019 (1960)

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