MilliporeSigma
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S7920

Sigma-Aldrich

Sodium fluoride

BioXtra, ≥99%

Linear Formula:
NaF
CAS Number:
Molecular Weight:
41.99
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

vapor pressure

1.4 mmHg ( 0 °C)

product line

BioXtra

assay

≥99%

impurities

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

mp

993 °C (lit.)

solubility

H2O: 1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.005%
sulfate (SO42-): ≤0.03%

cation traces

Al: ≤0.001%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.003%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.1%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES string

[F-].[Na+]

InChI

1S/FH.Na/h1H;/q;+1/p-1

InChI key

PUZPDOWCWNUUKD-UHFFFAOYSA-M

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Application

Sodium fluoride has been used:
  • as a source of fluoride ions, to analyse its impact on spermatogenesis and capacitation in vitro
  • as an additive in the extraction buffer for the isolation of nuclei, cytoplasmic and nuclear proteins
  • as a component of lysis buffer for the lysis of human ovarian adenocarcinoma OVCAR3 cells

Packaging

100, 500 g in poly bottle

Biochem/physiol Actions

Sodium fluoride (NaF) prevents dental caries, by catalysing the diffusion of calcium and phosphate and remineralizes the lesions. Fluoride affects spermatogenesis and capacitation process in the female reproductive tract. Fluoride induces oxidative stress, DNA damage in ovary ultimately affects the development of oocytes. Fluoride supplementation enhances bone mineral density. 18F-NaF is a radiotracer used in positron emission tomography (PET) to identify atherosclerotic lesions and other cardiac plaques.

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

Supplementary Hazards

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

More Documents

Quotes and Ordering

The influence of fluorides on mouse sperm capacitation
Dvorakova-Hortova K, et al.
Animal Reproduction Science, 108(1-2), 157-170 (2008)
Merging high-quality biochemical fractionation with a refined flow cytometry approach to monitor nucleocytoplasmic protein expression throughout the unperturbed mammalian cell cycle
Rosner M, et al.
Nature Protocols, 8(3), 602-602 (2013)
18F-sodium fluoride positron emission tomography for molecular imaging of coronary atherosclerosis based on computed tomography analysis
Kitagawa T, et al.
Atherosclerosis, 263(3), 385-392 (2017)
Toxicological Profile for Fluorides, Hydrogen Fluoride, and Fluorine (Update) (2011)
Dental caries
Selwitz RH, et al.
Lancet, 369(9555), 51-59 (2007)

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