155810

2-Methyltetrahydrofuran

BioRenewable, ReagentPlus^®, ≥99.5%, contains 150-400 ppm BHT as stabilizer

• Synonym(s): 2-MeTHF, Tetrahydro-2-methylfuran, Tetrahydrosilvan
• Empirical Formula (Hill Notation): C₅H₁₀O
• CAS Number: 96-47-9
• Molecular Weight: 86.13
• Beilstein/REAXYS Number: 102448
• EC Number: 202-507-4
• MDL number: MFCD00005367
• UNSPSC Code: 12352103
• PubChem Substance ID: 329750937
• NACRES: NA.21

Properties

• Quality Level: 100
• product line: ReagentPlus^®
• assay: ≥99.5%
• form: liquid
• contains: 150-400 ppm BHT as stabilizer
• expl. lim.: 0.34-6.3 %
• greener alternative product characteristics: Safer Solvents and Auxiliaries; Use of Renewable Feedstocks; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• impurities: ≤1.0% water (coulometr.); ≤100 ppm peroxide (as H₂O₂)
• refractive index: n20/D 1.406 (lit.)
• bp: 78-80 °C (lit.)
• mp: -136 °C
• density: 0.86 g/mL at 25 °C (lit.)
• greener alternative category: Aligned,
• SMILES string: CC1CCCO1
• InChI: 1S/C5H10O/c1-5-3-2-4-6-5/h5H,2-4H2,1H3
• InChI key: JWUJQDFVADABEY-UHFFFAOYSA-N

Description

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is biorenewable and thus it aligns with "Safer Solvents and Auxiliaries" and "Use of Renewable Feedstocks".  Click here  for more information.

2-Methyltetrahydrofuran (2-MTHF), a 2-methyl substituted tetrahydrofuran, is a biomass derived, environmentally favorable solvent alternative to tetrahydrofuran (THF), 1,4 Dioxane (Dioxane) and dichloromethane (DCM) for most industrial applications. Its polarity and Lewis base strength is intermediate between tetrahydrofuran (THF) and diethyl ether. It is a potential greener solvent alternative for organic synthesis and shows resistance to reduction by lithium making it a promising candidate as electrolytes in lithium batteries.

Application

2-Methyltetrahydrofuran may be used as an alternative solvent to:
THF in organometallic reactions

• Grignard
• Reformantsky
• Lithiation
• Hydride Reduction
• Metal-Catalyzed Coupling (Heck, Stile, Suzuki)

Dichloromethane for Biphasic Reactions:

• Alkylation
• Amidation
• Nucleophilic Substitution

Features and Benefits

• Made from Renewable Resource - furfural derived from agricultural byproducts
• High boiling point
• Clean organic-water phase separation
• Reduced energy to recover
  

Other Notes

To see other BioRenewable or Greener Solvents

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02,GHS05,GHS07
• signalword: Danger
• hcodes: H225,H302,H315,H318
• pcodes: P210 - P233 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2
• supp_hazards: EUH019
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 14.0 °F - closed cup
• flash_point_c: -10.0 °C - closed cup